3-(2,4-Difluorophenyl)-3H-[1,2,3]triazolo[4,5-b]pyridine CAS 62051-90-5
| CAS No. | 62051-90-5 |
| Molecular Formula | C11H6F2N4 |
| Molecular Weight | 232.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-(2,4-Difluorophenyl)-3H-[1,2,3]triazolo[4,5-b]pyridine (CAS 62051-90-5), molecular formula C11H6F2N4 and molecular weight 232.19 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-(2,4-Difluorophenyl)-3H-[1,2,3]triazolo[4,5-b]pyridine (C11H6F2N4) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H6F2N4 |
| Molecular Weight | 232.19 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1974 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Difluorophenyl Standards
- 6-(2,4-Difluorophenyl)-2-hydroxynicotinonitrile (CAS 1204296-69-4)
- 2-(2,4-Difluorophenyl)oxazolo[4,5-b]pyridine (CAS 52333-52-5)
- 2-(2,5-Difluorophenyl)oxazolo[4,5-b]pyridine (CAS 52333-66-1)
- 2-(2,6-Difluorophenyl)oxazolo[4,5-b]pyridine (CAS 52333-73-0)
- 3-(2,5-Difluorophenyl)-3H-[1,2,3]triazolo[4,5-b]pyridine (CAS 62052-04-4)
- 3-(2,6-Difluorophenyl)-3H-[1,2,3]triazolo[4,5-b]pyridine (CAS 62052-06-6)
- 8-(2,3-difluorophenyl)-7H-purine (CAS 878287-57-1)
- (2,4-Difluorophenyl)(m-tolyl)methanone (CAS 1094311-95-1)
Recommended Standards
- 3-(1,3-Benzodioxol-5-yl)-1H-pyrazole-5-carboxylic acid (CAS 890621-48-4)
- 2-Phenylfuran-3,4-dicarboxylic acid (CAS 240116-46-5)
- 2-methyl-4-[(4-nitrophenyl)methylidene]-4,5-dihydro-1,3-oxazol-5-one (CAS 78312-00-2)
- 3-(3,6-Dioxo-1,2,3,6-tetrahydropyridazin-1-yl)benzoic acid (CAS 87565-86-4)
- 145026-81-9 161W380R06 Propoxycarbazone [ISO] Benzoic acid, 2-((((4,5-dihydro-4-methyl-5-oxo-3-propoxy-1H-1,2,4-triazol-1-yl)carbonyl)amino)sulfonyl)-, methyl ester Propoxycarbazone UNII-161W380R06 (CAS 145026-81-9)
- (S)-2-amino-2-(4-fluoro-3-methylphenyl)ethan-1-ol (CAS 1213127-92-4)
- 3-(3-Fluorophenyl)-2-(5-methyl-1h-1,2,3,4-tetrazol-1-yl)propanoic acid (CAS 1118787-20-4)
- 2-Bromo-5-ethoxy-4-hydroxy-3-iodobenzaldehyde (CAS 1151530-41-4)
- tert-Butyl (3R,4S)-3-(4-chlorophenyl)-4-(hydroxymethyl)pyrrolidine-1-carboxylate (CAS 1354484-78-8)
- 7-Fluoro-2-(trifluoromethyl)benzo[d]thiazole (CAS 1188165-54-9)
- 3,5-Difluoro-4-(1-pyrrolidinylcarbonyl)phenylboronic acid (CAS 1264616-16-1)
- (R)-4-(tert-pentyl)-2-(pyrrolidin-2-yl)phenol (CAS 1213956-70-7)
- 2-(3-Bromo-5-chloro-4-(trifluoromethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2621936-28-3)
- Epidermal Growth Factor Receptor Peptide (985-996) (CAS 96249-43-3)
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