2-Chloro-6-(4-fluorophenyl)-4-phenylnicotinonitrile CAS 1205028-27-8
| CAS No. | 1205028-27-8 |
| Molecular Formula | C18H10ClFN2 |
| Molecular Weight | 308.74 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 2-Chloro-6-(4-fluorophenyl)-4-phenylnicotinonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
2-Chloro-6-(4-fluorophenyl)-4-phenylnicotinonitrile (CAS 1205028-27-8), molecular formula C18H10ClFN2 and molecular weight 308.74 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 2-Chloro-6-(4-fluorophenyl)-4-phenylnicotinonitrile (C18H10ClFN2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 14.0, corresponding to approximately 14 ring(s) or double-bond equivalent(s). With a molecular weight of 308.74 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H10ClFN2 |
| Molecular Weight | 308.74 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
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- ethyl 1-(5-chloro-2-fluorophenyl)-1H,4H,5H,6H-cyclopenta[c]pyrazole-3-carboxylate (CAS 1909309-82-5)
- ethyl 1-(4-chloro-2-fluorophenyl)-1H,4H,5H,6H-cyclopenta[c]pyrazole-3-carboxylate (CAS 1909317-05-0)
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Recommended Standards
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- N-(5-Amino-2-fluorophenyl)-2-(2-chlorophenoxy)-propanamide (CAS 1020056-97-6)
- 4-(Benzyloxy)-6-cyanopyridine-2-sulfonyl chloride (CAS 1393572-69-4)
- 2-(4-Fluoro-1H-pyrazol-1-yl)ethanamine (CAS 1174306-39-8)
- (2-methyloxetan-3-yl)methanol (CAS 2090302-35-3)
- 2-Fluoro-2-phenylethan-1-ol (CAS 2932-58-3)
- N1-(1-Methyl-3-(trifluoromethyl)-1H-1,2,4-triazol-5-yl)ethane-1,2-diamine (CAS 1785763-68-9)
- 5-(3-Chlorophenoxymethyl)thiophene-2-carboxylic acid (CAS 74556-81-3)
- Des-Ala21-Tirzepatide (CAS CATO-CPTD788952)
- 9-Nitro-2,3,4,5-tetrahydro-1h-1,4-benzodiazepin-5-one (CAS 328546-65-2)
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- (6S,12aR)-3,10-dibromo-6-phenyl-12,12a-dihydro-6H-benzo[5,6][1,3]oxazino[3,4-a]indole (CAS 1585969-16-9)
- Atrial Natriuretic Polypeptide (4-28), human (CAS 95896-08-5)
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