4-(1,1-Difluoroethyl)cyclohexan-1-one CAS 1205751-18-3
| CAS No. | 1205751-18-3 |
| Molecular Formula | C8H12F2O |
| Molecular Weight | 162.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 4-(1,1-Difluoroethyl)cyclohexan-1-one (C8H12F2O) is characterized by a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
4-(1,1-Difluoroethyl)cyclohexan-1-one (CAS 1205751-18-3), molecular formula C8H12F2O and molecular weight 162.18 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-(1,1-Difluoroethyl)cyclohexan-1-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H12F2O |
| Molecular Weight | 162.18 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Stable under recommended storage conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
Related Difluoroethyl Standards
- [1-(2,2-difluoroethyl)-1H-pyrazol-3-yl]methanol (CAS 1260659-08-2)
- (1-(2,2-Difluoroethyl)-1h-pyrazol-5-yl)methanol (CAS 1262865-35-9)
- [1-(2,2-difluoroethyl)-1H-pyrazol-4-yl]methanol (CAS 1341536-55-7)
- [1-(2,2-difluoroethyl)-1h-1,2,4-triazol-5-yl]methanol (CAS 265643-98-9)
- 1-(2,2-Difluoroethyl)piperidin-4-one (CAS 1178833-49-2)
- 1-(2,2-Difluoroethyl)piperidin-3-one (CAS 150-85-7)
- 1-(2,2-Difluoroethyl)-3-methyl-1H-pyrazol-4-amine (CAS 1006462-68-5)
- 1-(2,2-Difluoroethyl)-5-methyl-1h-pyrazol-3-amine (CAS 1006486-89-0)
Recommended Standards
- 3-(3-Methoxypropoxy)propanoic acid (CAS 1184834-40-9)
- 1-(4,4-Difluorocyclohexyl)ethan-1-one (CAS 121629-16-1)
- (5R,6R)-2,2-dimethyl-1,3-dioxepane-5,6-diol (CAS 1151512-26-3)
- (S)-7,7-Difluorooctahydropyrrolo[1,2-a]pyrazine (CAS 1222710-79-3)
- N-tert-Butyloxycarbonyl-L-pipecolic Acid 2,6-Dimethyl-benzenamine Ester (CAS 1391068-04-4)
- 4-(2,2-Difluoroethoxy)-2-methylaniline (CAS 937602-96-5)
- 3-(tert-butoxy)-2-(1H-pyrazol-1-yl)cyclobutan-1-amine (CAS 1909305-47-0)
- 2-Chloro-5-fluorobenzo[d]thiazole (CAS 154327-27-2)
- 3-Bromo-9-n-octyl-9H-carbazole (CAS 628337-00-8)
- (R)-Methyl morpholine-3-carboxylate hydrochloride (CAS 1187929-55-0)
- 1-Isopropoxy-4-(trifluoromethoxy)-benzene (CAS 1030471-18-1)
- 2-(3-Chlorophenoxy)tetrahydrofuran (CAS 61632-63-1)
- 2-(3-Fluorophenyl)thiazole-5-carbaldehyde (CAS 914348-84-8)
- Liraglutide-d8 Tritrifluoroacetate (CAS CATO-C4X-199223)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com