1-(2,2-Difluoroethyl)piperidin-4-one CAS 1178833-49-2
| CAS No. | 1178833-49-2 |
| Molecular Formula | C7H11F2NO |
| Molecular Weight | 163.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 1-(2,2-Difluoroethyl)piperidin-4-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
1-(2,2-Difluoroethyl)piperidin-4-one (CAS 1178833-49-2), molecular formula C7H11F2NO and molecular weight 163.17 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-(2,2-Difluoroethyl)piperidin-4-one (C7H11F2NO) is characterized by an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C7H11F2NO |
| Molecular Weight | 163.17 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Difluoroethyl Standards
- 1-(2,2-Difluoroethyl)piperidin-3-one (CAS 150-85-7)
- [1-(2,2-difluoroethyl)-1h-1,2,4-triazol-5-yl]methanol (CAS 265643-98-9)
- N-(2,2-difluoroethyl)cyclohexanamine (CAS 1184838-47-8)
- 1,1-Difluoroethyl 2,2,2-Trifluoroethyl Ether (CAS 25352-91-4)
- 3-(1,1-Difluoroethyl)-3-Methyloxolan-2-One (CAS 131147-39-2)
- 1-(2,2-difluoroethyl)cyclobutane-1-carboxylic acid (CAS 1529329-33-6)
- 1-(2,2-Difluoroethyl)piperazin-2-one (CAS 1548396-54-8)
- methyl 1-(1,1-difluoroethyl)cyclopropane-1-carboxylate (CAS 1909319-67-0)
Recommended Standards
- (2E)-3-(6-Methylpyridin-3-yl)prop-2-enoic acid (CAS 117830-17-8)
- 5-Acetyl-2,3-dihydro-1H-pyrrolizin-1-one (CAS 118097-03-3)
- (2S,3S,4S,5S)-2-(Hydroxymethyl)-3,4,5-piperidinetriol (CAS 117821-07-5)
- (S)-Isoindoline-1-carboxylic Acid (CAS 118312-39-3)
- Ethyl 3-aminocyclohexanecarboxylate sulfate (CAS 1206675-61-7)
- 5-Methyl-N-(4-(pyridin-3-yl)thiazol-2-yl)isoxazole-3-carboxamide (CAS 941903-04-4)
- Cefuroxime Sodium EP Impurity D (CAS 76598-06-6)
- H-Gly-Gly-Arg-Ser-Pro-Ala-Met-Pro-Glu-OH trifluoroacetate salt (CAS 2022956-40-5)
- Propanal, 2-methyl-, polymer with 1-piperazineethanol (CAS 72333-08-5)
- 3,5-dibromo-4-ethylbenzoic acid (CAS 1803601-91-3)
- 1,1,1,3,3,3-Hexaphenyldisiloxane (CAS 1829-40-9)
- Lotilaner Impurity 27 (E-Isomer) (CAS 2758907-88-7)
- 3-(2-AMINO-ETHYL)-ANILINE (CAS 76935-75-6)
- Endo-38a-Pro-Exenatide trifluoroacetate salt (CAS 1678416-95-9)
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