6-Trifluoromethyl-1h-pyrazine-2-thione CAS 1206523-94-5
| CAS No. | 1206523-94-5 |
| Molecular Formula | C5H3F3N2S |
| Molecular Weight | 180.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 6-Trifluoromethyl-1h-pyrazine-2-thione is closely related to a nitrile group, sulfur-containing functionality, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
6-Trifluoromethyl-1h-pyrazine-2-thione (CAS 1206523-94-5) is a high-purity analytical reference standard with the molecular formula C5H3F3N2S and a molecular weight of 180.15 g/mol.
Structurally, 6-Trifluoromethyl-1h-pyrazine-2-thione (C5H3F3N2S) contains a nitrile group, sulfur-containing functionality, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 180.15 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 6-Trifluoromethyl-1h-pyrazine-2-thione under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C5H3F3N2S |
| Molecular Weight | 180.15 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Trifluoromethyl Standards
- 6-(Trifluoromethyl)pyridazine-3-thiol (CAS 1206524-42-6)
- 5-Trifluoromethyl-3h-pyrazine-2-thione (CAS 1206524-59-5)
- 2-((Trifluoromethyl)thio)pyrimidine (CAS 129550-10-3)
- 4-(trifluoromethyl)thiophene-3-carbaldehyde (CAS 1363512-23-5)
- 4-(Trifluoromethyl)-2-pyrimidinethiol (CAS 136547-17-6)
- 4-(Trifluoromethyl)thiophene-2-carbaldehyde (CAS 1367866-60-1)
- 2-(Trifluoromethyl)pyrimidine-4-thiol (CAS 672-43-5)
- 5-(Trifluoromethyl)thiophene-2-carbaldehyde (CAS 901767-00-8)
Recommended Standards
- 7,8-Difluoroquinolin-4-amine (CAS 1189107-49-0)
- 6,7-difluoronaphthalen-1-ol (CAS 1188555-99-8)
- 2-(3,4-Difluorophenyl)-1h-imidazole (CAS 1184472-89-6)
- 5,8-Difluoroquinolin-6-amine (CAS 1242094-78-5)
- 2-(6-Cyano-2H-1,3-benzodioxol-5-yl)acetic acid (CAS 1315577-19-5)
- N-(2,4-dimethylphenyl)-3-hydroxy-4-((2-hydroxyphenyl)diazenyl)-2-naphthamide (CAS 523-67-1)
- tert-Butyl(((5S)-5-((4-fluorophenoxy)methyl)tetrahydrofuran-2-yl)oxy)dimethylsilane (CAS 220623-68-7)
- Prasugrel Impurity 12 (CAS 1100905-45-0)
- L-Veratrylglycine (CAS 32161-30-1)
- N-(2,2-Dimethoxyethyl)-4-methoxy-N-methyl-1,3-benzodioxole-5-methanamine (CAS 108261-02-5)
- 3-Bromo-2,4-dichloro-6-(trifluoromethyl)quinoline (CAS 1447953-41-4)
- N-(4-fluoro-3-methylphenyl)-4,5-dihydrothiazol-2-amine (CAS 866153-25-5)
- Benzyl 2-methylpyrrolidine-1-carboxylate (CAS 886576-75-6)
- Semaglutide impurity 93 (CAS CATO-C4X-222693)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
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