5-Trifluoromethyl-3h-pyrazine-2-thione CAS 1206524-59-5
| CAS No. | 1206524-59-5 |
| Molecular Formula | C5H3F3N2S |
| Molecular Weight | 180.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 5-Trifluoromethyl-3h-pyrazine-2-thione is closely related to a nitrile group, sulfur-containing functionality, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
5-Trifluoromethyl-3h-pyrazine-2-thione (CAS 1206524-59-5) is a high-purity analytical reference standard with the molecular formula C5H3F3N2S and a molecular weight of 180.15 g/mol.
Structurally, 5-Trifluoromethyl-3h-pyrazine-2-thione (C5H3F3N2S) contains a nitrile group, sulfur-containing functionality, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 180.15 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-Trifluoromethyl-3h-pyrazine-2-thione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H3F3N2S |
| Molecular Weight | 180.15 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Trifluoromethyl Standards
- 6-Trifluoromethyl-1h-pyrazine-2-thione (CAS 1206523-94-5)
- 6-(Trifluoromethyl)pyridazine-3-thiol (CAS 1206524-42-6)
- 2-((Trifluoromethyl)thio)pyrimidine (CAS 129550-10-3)
- 4-(trifluoromethyl)thiophene-3-carbaldehyde (CAS 1363512-23-5)
- 4-(Trifluoromethyl)-2-pyrimidinethiol (CAS 136547-17-6)
- 4-(Trifluoromethyl)thiophene-2-carbaldehyde (CAS 1367866-60-1)
- 2-(Trifluoromethyl)pyrimidine-4-thiol (CAS 672-43-5)
- 5-(Trifluoromethyl)thiophene-2-carbaldehyde (CAS 901767-00-8)
Recommended Standards
- 5,8-Difluoroquinolin-6-amine (CAS 1242094-78-5)
- 5,6-Difluoroquinolin-8-amine (CAS 1242094-79-6)
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- 2-(3,5-Difluorophenyl)imidazole (CAS 1247441-83-3)
- 3-Methyl-8-(pentylamino)-7-propyl-3,7-dihydro-1H-purine-2,6-dione (CAS 941886-03-9)
- Diethyl pyridin-2-ylphosphonate (CAS 23081-78-9)
- 4-(4-Methoxycarbonyl-phenyl)-3,6-dihydro-2H-pyridine-1-carboxylic acid tert-butyl ester (CAS 406235-16-3)
- 5-(Benzyloxy)-2-fluorobenzoic acid (CAS 1148146-72-8)
- 5-Chloro-6-methyl-N1-phenylbenzene-1,2-diamine (CAS 79759-93-6)
- 6-Hydroxymethyl-6,7-dihydro-5h,9h-imidazo[1,5-a][1,4]diazepine-8-carboxylic acid tert-butyl ester (CAS 1250999-49-5)
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