2-Fluoro-3-(trifluoromethyl)pyrazine CAS 1206524-60-8
| CAS No. | 1206524-60-8 |
| Molecular Formula | C5H2F4N2 |
| Molecular Weight | 166.08 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-Fluoro-3-(trifluoromethyl)pyrazine (CAS 1206524-60-8) is a high-purity analytical reference standard with the molecular formula C5H2F4N2 and a molecular weight of 166.08 g/mol.
2-Fluoro-3-(trifluoromethyl)pyrazine (C5H2F4N2) contains a nitrile group, fluorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-Fluoro-3-(trifluoromethyl)pyrazine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H2F4N2 |
| Molecular Weight | 166.08 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Fluoro Standards
- 5-Fluoro-2-(trifluoromethyl)pyrimidine (CAS 100345-66-2)
- 2-Fluoro-4-(trifluoromethyl)pyrimidine (CAS 1093098-55-5)
- 3-Fluoro-6-(trifluoromethyl)pyridazine (CAS 1206524-32-4)
- 2-Fluoro-6-trifluoromethyl-pyrazine (CAS 1206524-47-1)
- 2-Fluoro-5-(trifluoromethyl)pyrimidine (CAS 1214344-68-9)
- 2-Fluoro-5-(trifluoromethyl)pyrazine (CAS 1220799-65-4)
- 3-Fluoro-2-nitrobenzonitrile (CAS 1000339-52-5)
- 4-Fluoro-3-nitrobenzonitrile (CAS 1009-35-4)
Recommended Standards
- ((hydroxy(methyl)phosphoryl)methyl)glycine (CAS 70291-04-2)
- 1H-Purine-2,6,8(3H)-trione (CAS 67708-21-8)
- 2,3,5,6-Tetrafluorophenol (CAS 769-39-1)
- 2-Hydroxyfuro[3,4-b]pyrazine-5,7-dione (CAS 73403-50-6)
- n-(3-Methoxybenzyl)-2-((5-methyl-1h-benzo[d]imidazol-2-yl)thio)acetamide (CAS 851689-66-2)
- 1-(3-methoxypyridin-4-yl)ethan-1-amine (CAS 1196733-04-6)
- (R)-3-Amino-1-methyl-5-phenyl-1,3-dihydro-2H-benzo[e][1,4]diazepin-2-one (CAS 103343-65-3)
- 2-(Pyrrolidin-3-ylmethyl)pyrazine (CAS 914299-91-5)
- 1-Methyl-3,4-dihydroisoquinoline (CAS 2412-58-0)
- Tert-butyl ((6-oxo-1,6-dihydropyridin-3-yl)methyl)carbamate (CAS 1253654-25-9)
- 2-((4-(Isopropyl(methyl)amino)cyclohexyl)amino)ethanol (CAS 1353958-41-4)
- (S)-2-(3,4-Dichlorophenyl)pent-4-enoic acid 147643-57-0 4531AD C11H10Cl2O2 (CAS 147643-57-0)
- 2-(Bromomethyl)-7-phenylbenzo[d]thiazole (CAS 1227629-45-9)
- Glucagon (1-29) (CAS 16941-32-5)
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