Imatinib Impurity 83 CAS 1206604-20-7
| CAS No. | 1206604-20-7 |
| Molecular Formula | C16H13BrN4 |
| Molecular Weight | 341.21 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Imatinib Impurity 83.
As a process- or degradation-related impurity, Imatinib Impurity 83 (CAS 1206604-20-7, C16H13BrN4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Imatinib Impurity 83 (C16H13BrN4) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Imatinib Impurity 83 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H13BrN4 |
| Molecular Weight | 341.21 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 4 |
Related Imatinib Standards
- Imatinib Impurity 76 (CAS CATO-C4X-106876)
- Imatinib Impurity 47 (CAS CATO-C4X-106847)
- Imatinib Impurity 89 (CAS CATO-C4X-106889)
- Imatinib Impurity 95 (CAS CATO-C4X-106895)
- Imatinib Impurity 74 (CAS CATO-C4X-106874)
- Imatinib Impurity 99 (CAS 189037-78-3)
- Imatinib Impurity 64 (CAS 1356565-47-3)
- Imatinib Impurity 94 (CAS CATO-C4X-106894)
Recommended Standards
- N-[4-(tert-butyl)phenyl]-2,6-dichloro-5-fluoronicotinamide (CAS 680217-83-8)
- Ibandronic Impurity 7 (CAS CATO-C4X-22447)
- N-[2-Amino-4-(4-bromophenyl)-1H-imidazol-1-yl]-N-[(E)-phenylmethylidene]amine (CAS 275358-95-7)
- 5-Amino-N-(4-bromophenyl)-2-methylbenzene-1-sulfonamide (CAS 114500-28-6)
- Tegoprazan Impurity 135 (CAS CATO-C4X-2297135)
- Kukoamine Impurity 10 (CAS CATO-C4X-229610)
- Epinephrine Impurity 44 (CAS 2947-00-4)
- (2RS,3RS)-3-(2-Ethoxy-d5-phenoxy)-2-mesyloxy-3-phenyl-1-propanol (CAS 1189680-85-0)
- 3-Bromo-N,N-dimethylimidazo[1,2-a]pyrazin-8-amine (CAS 787590-55-0)
- 6-Bromo-2-(4-methylpiperazin-1-yl)quinoline (CAS 124783-03-5)
- 9-Butyl-6-(isopropylthio)-9H-purin-2-amine (CAS 56964-82-0)
- N-(2,6-dichloro-4-pyridyl)-n-[5-(methylthio)-4h-1,2,4-triazol-3-yl]urea (CAS 287174-87-2)
- 3-((Tert-butoxycarbonyl)(methyl)amino)-2-(3-methoxybenzyl)propanoic acid (CAS 886364-83-6)
- Erythropoietin Mimetic Peptide Sequence 20 (CAS 203397-62-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com