1-(2-((4-(Pyrimidin-2-yl)piperazin-1-yl)sulfonyl)ethyl)-3-(thiophen-2-yl)urea CAS 1207005-68-2
| CAS No. | 1207005-68-2 |
| Molecular Formula | C15H20N6O3S2 |
| Molecular Weight | 396.49 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(2-((4-(Pyrimidin-2-yl)piperazin-1-yl)sulfonyl)ethyl)-3-(thiophen-2-yl)urea.
1-(2-((4-(Pyrimidin-2-yl)piperazin-1-yl)sulfonyl)ethyl)-3-(thiophen-2-yl)urea (CAS 1207005-68-2), molecular formula C15H20N6O3S2 and molecular weight 396.49 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-(2-((4-(Pyrimidin-2-yl)piperazin-1-yl)sulfonyl)ethyl)-3-(thiophen-2-yl)urea (C15H20N6O3S2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-(2-((4-(Pyrimidin-2-yl)piperazin-1-yl)sulfonyl)ethyl)-3-(thiophen-2-yl)urea meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H20N6O3S2 |
| Molecular Weight | 396.49 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Nitrogen Atoms | 6 |
| Sulfur Atoms | 2 |
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- Ethyl 4-(2-(2-(pyrimidin-2-ylamino)thiazol-4-yl)acetamido)piperidine-1-carboxylate (CAS 1226429-72-6)
- 4-Oxo-6-((pyrimidin-2-ylthio)methyl)-4H-pyran-3-yl 4-nitrobenzoate (CAS 877636-42-5)
- (E)-1-(4-(pyrimidin-2-yloxy)phenyl)-3-((3-(trifluoromethyl)phenyl)amino)prop-2-en-1-one (CAS 1164457-65-1)
- 1-(4-(4-(2-(Pyrimidin-2-ylamino)thiazole-4-carbonyl)piperazin-1-yl)phenyl)ethan-1-one (CAS 1251562-91-0)
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Recommended Standards
- 5-(((6-(4-Ethoxyphenyl)pyridazin-3-yl)thio)methyl)-3-(thiophen-2-yl)-1,2,4-oxadiazole (CAS 1115285-44-3)
- Benzo[c][1,2,5]thiadiazol-5-yl(4-(benzo[d]thiazol-2-yloxy)piperidin-1-yl)methanone (CAS 1251691-84-5)
- Landiolol Impurity 63 (CAS CATO-C4X-263163)
- Alfuzosin-d7 (CAS 1346746-88-0)
- 1,1,3-Triphenylpropargyl Alcohol (CAS 1522-13-0)
- (4,6-Diphenyl-1,3,5-triazin-2-yl)boronic acid (CAS 1251825-65-6)
- Prop-2-en-1-yl n-[4-(hydroxymethyl)phenyl]carbamate (CAS 914094-82-9)
- 4-Hydroxy-4-(1H-imidazol-4-yl)piperidine-1-carboxylic acid tert-butyl ester (CAS 173469-30-2)
- 1’-Boc-spiro[indoline-3,4’-piperidin]-2-one (CAS 252882-60-3)
- 2-(Hydroxymethyl)benzo[d]oxazole-4-acetic acid (CAS 1806284-85-4)
- 2-(4-Isopropylphenyl)ethanol (CAS 10099-57-7)
- 1-[(2-bromophenyl)methyl]cyclopropane-1-carboxylic acid (CAS 1483329-91-4)
- 1-Chloro-2-fluoro-3-(trifluoromethyl)benzene (CAS 1099597-93-9)
- [Tyr15] Fibrinopeptide B, human (CAS 125455-56-3)
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