4-Chloro-5-iodo-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidine CAS 1207543-30-3
| CAS No. | 1207543-30-3 |
| Molecular Formula | C12H17ClIN3OSi |
| Molecular Weight | 409.73 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-Chloro-5-iodo-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidine is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine/iodine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
4-Chloro-5-iodo-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidine (CAS 1207543-30-3) is a high-purity analytical reference standard with the molecular formula C12H17ClIN3OSi and a molecular weight of 409.73 g/mol.
4-Chloro-5-iodo-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidine (C12H17ClIN3OSi) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine/iodine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-Chloro-5-iodo-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H17ClIN3OSi |
| Molecular Weight | 409.73 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl/I-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- 4-Chloro-6-iodo-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidine (CAS 1404299-81-5)
- 5-Chloro-3-iodo-1-{[2-(trimethylsilyl)ethoxy]methyl}-1h-pyrazolo[4,3-b]pyridine (CAS 2170597-67-6)
- 3-Chloro-2-({4-[(5-nitropyridin-2-yl)oxy]phenyl}methyl)-5-(trifluoromethyl)pyridine (CAS 338393-30-9)
- 5-Benzyl-3-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-3aH,4H,5H,6H,6aH-pyrrolo[3,4-d][1,2]oxazole-4,6-dione (CAS 339030-07-8)
- 8-(2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}ethyl)-2,4,5,8,10-pentaazatricyclo[7.4.0.0^{2,6}]trideca-1(9),3,5,10,12-pentaen-7-one (CAS 338412-01-4)
- (S)-(6-chloro-1-(hydroxymethyl)-1,2,3,4-tetrahydronaphthalen-1-yl)methyl 4-bromobenzoate (CAS 1883726-75-7)
- 3-Chloro-5-(trifluoromethyl)-2-{4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenoxy}pyridine (CAS 1024231-01-3)
- Ethyl 2-((2-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-5-fluoro-6-methylpyrimidin-4-yl)thio)acetate (CAS 1823183-41-0)
Recommended Standards
- 4-Bromo-2-((4-chlorophenyl)sulfonyl)-N,N-dimethylthiazole-5-carboxamide (CAS 1000576-62-4)
- 2,3,4,6-Tetrabromophenol (CAS 14400-94-3)
- 4,4''-Dichloro-5'-(4-chlorophenyl)-1,1':3',1''-terphenyl (CAS 6326-61-0)
- 7α-Hydroxycholesterol-d7 (CAS 349553-94-2)
- Ethyl 4-(2-carbamoylphenoxy)piperidine-1-carboxylate (CAS 1956310-90-9)
- 2-Propoxypropan-1-amine (CAS 883533-22-0)
- (2E)-4-Oxo-4-[[2-(piperidin-1-ylsulfonyl)ethyl]-(pyridin-4-ylmethyl)amino]but-2-enoic acid (CAS 929863-40-1)
- Sodium n-dodecyl sulfate (CAS 151-21-3)
- 5-Aminothiazole-4-carbaldehyde (CAS 1823328-96-6)
- ethyl 5-amino-3,4-dimethyl-thieno[2,3-c]pyridazine-6-carboxylate (CAS 717840-40-9)
- 5-(4-Methoxyphenyl)nicotinonitrile (CAS 1268095-82-4)
- (2,6-Dichloro-3-isopropoxyphenyl)(methyl)sulfane (CAS 2624417-07-6)
- 2-Hydrazinyl-4-(4-methoxyphenyl)-5-methylthiazole (CAS 886494-21-9)
- Semaglutide impurity 46 (CAS CATO-C4X-222646)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com