3-Chloro-2-({4-[(5-nitropyridin-2-yl)oxy]phenyl}methyl)-5-(trifluoromethyl)pyridine CAS 338393-30-9
| CAS No. | 338393-30-9 |
| Molecular Formula | C18H11ClF3N3O3 |
| Molecular Weight | 409.75 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
3-Chloro-2-({4-[(5-nitropyridin-2-yl)oxy]phenyl}methyl)-5-(trifluoromethyl)pyridine (CAS 338393-30-9) is a high-purity analytical reference standard with the molecular formula C18H11ClF3N3O3 and a molecular weight of 409.75 g/mol.
Based on its molecular formula C18H11ClF3N3O3, 3-Chloro-2-({4-[(5-nitropyridin-2-yl)oxy]phenyl}methyl)-5-(trifluoromethyl)pyridine contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 409.75 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H11ClF3N3O3 |
| Molecular Weight | 409.75 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- 5-Benzyl-3-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-3aH,4H,5H,6H,6aH-pyrrolo[3,4-d][1,2]oxazole-4,6-dione (CAS 339030-07-8)
- 8-(2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}ethyl)-2,4,5,8,10-pentaazatricyclo[7.4.0.0^{2,6}]trideca-1(9),3,5,10,12-pentaen-7-one (CAS 338412-01-4)
- 4-Chloro-5-iodo-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidine (CAS 1207543-30-3)
- 4-Chloro-6-iodo-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidine (CAS 1404299-81-5)
- 5-Chloro-3-iodo-1-{[2-(trimethylsilyl)ethoxy]methyl}-1h-pyrazolo[4,3-b]pyridine (CAS 2170597-67-6)
- Ethyl 2-((2-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-5-fluoro-6-methylpyrimidin-4-yl)thio)acetate (CAS 1823183-41-0)
- 4-Chloro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidine (CAS 1830311-70-0)
- 1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-N-[(4-methoxyphenyl)methyl]-1H-pyrrole-2-carboxamide (CAS 338397-63-0)
Recommended Standards
- 1-[(2H-1,3-Benzodioxol-5-yl)methyl]-5-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-1,4-dihydropyrimidin-4-one (CAS 477888-17-8)
- 1-(4-Chlorophenyl)-2,6-dioxo-N-(3-(trifluoromethyl)phenyl)-1,2,3,6-tetrahydropyrimidine-4-carboxamide (CAS 861212-24-0)
- N-[(Z)-2-[4-(4-Chlorophenyl)-5-(trifluoromethyl)-4H-1,2,4-triazol-3-yl]-2-nitroethenyl]aniline (CAS 400079-82-5)
- 4,4''-Dichloro-5'-(4-chlorophenyl)-1,1':3',1''-terphenyl (CAS 6326-61-0)
- 7-Methyl-[1,2,4]triazolo[1,5-a]pyrimidine-2-carboxylic acid (CAS 438031-05-1)
- 7-((2-Chlorophenyl)(methoxy)methyl)-2,3,4,5-tetrahydrobenzo[f][1,4]oxazepine (CAS 1160245-49-7)
- 2-(Aminomethyl)-5-chloropyridine (CAS 67938-76-5)
- 2-(tert-Butoxy)-5-cyclopropoxy-N-methylaniline (CAS 1243448-44-3)
- 2-(Vinyloxy)aniline (CAS 7707-00-8)
- 1-[2-(trifluoromethyl)phenyl]propan-2-amine hydrochloride (CAS 670-03-1)
- 6-Hydrazinyl-5-methyl-4,5-dihydropyridazin-3(2H)-one (CAS 150711-46-9)
- (2-Bromobenzyl)(3-fluorophenyl)sulfane (CAS 1001161-71-2)
- Olanzapine Pamoic Acid (CAS 221373-09-7)
- Semaglutide Impurity 164 (CAS CATO-C4X-2226164)
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