5-Chloro-2,4-difluorobenzenethiol CAS 1208076-87-2
| CAS No. | 1208076-87-2 |
| Molecular Formula | C6H3ClF2S |
| Molecular Weight | 180.60 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 5-Chloro-2,4-difluorobenzenethiol is closely related to sulfur-containing functionality, fluorine/chlorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
5-Chloro-2,4-difluorobenzenethiol (CAS 1208076-87-2), molecular formula C6H3ClF2S and molecular weight 180.60 g/mol, is a CATO reference standard with documented purity and traceability.
5-Chloro-2,4-difluorobenzenethiol (C6H3ClF2S) contains sulfur-containing functionality, fluorine/chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-Chloro-2,4-difluorobenzenethiol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H3ClF2S |
| Molecular Weight | 180.60 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 6-Chloro-2,3-difluorothiophenol (CAS 1208075-95-9)
- 4-Chloro-2,5-difluorobenzenethiol (CAS 1208076-25-8)
- 2-Chloro-3,6-difluorothiophenol (CAS 1208076-51-0)
- 4-Chloro-2,6-difluorothiophenol (CAS 1208077-41-1)
- 2-Chloro-4,5-difluorobenzenethiol (CAS 1208077-95-5)
- 3-Chloro-2,4-difluorobenzenethiol (CAS 1208078-21-0)
- 2-Chloro-4,6-difluorobenzenethiol (CAS 1242339-38-3)
- 2-Chloro-3,4-difluorobenzenethiol (CAS 1805223-41-9)
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- (2E)-1-(2,4-Dimethoxyphenyl)-3-(2-methylphenyl)prop-2-en-1-one (CAS 415686-07-6)
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- 1-(Methylthio)isoquinolin-3(4H)-one (CAS 36068-76-5)
- Methyl 2-(3-(aminomethyl)bicyclo[1.1.1]Pentan-1-yl)acetate (CAS 2168581-05-1)
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- 6-(4-Bromophenyl)picolinaldehyde (CAS 65219-26-3)
- Bis(4-bromophenyl)amine (CAS 16292-17-4)
- N6-(4-Amino-1-β-D-Ribofuranosyl-2(1H)-Pyrimidinylidene)-L-Lysine (CAS 144796-96-3)
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