4-Chloro-2,5-difluorobenzenethiol CAS 1208076-25-8

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-Chloro-2,5-difluorobenzenethiol.

4-Chloro-2,5-difluorobenzenethiol (CAS 1208076-25-8), molecular formula C6H3ClF2S and molecular weight 180.60 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 4-Chloro-2,5-difluorobenzenethiol (C6H3ClF2S) is characterized by sulfur-containing functionality, fluorine/chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 4-Chloro-2,5-difluorobenzenethiol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

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