Oclacitinib Impurity 21 CAS 1208319-28-1
| CAS No. | 1208319-28-1 |
| Molecular Formula | C22H29N5O4S2 |
| Molecular Weight | 491.63 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Oclacitinib Impurity 21 (CAS 1208319-28-1), a pharmacopoeial impurity reference standard (molecular formula C22H29N5O4S2, MW 491.63 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, Oclacitinib Impurity 21 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 491.63 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Oclacitinib Impurity 21 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H29N5O4S2 |
| Molecular Weight | 491.63 g/mol |
| Purity | ≥95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 2 |
Related Oclacitinib Standards
- Oclacitinib Impurity 22 (CAS 1208319-34-9)
- Oclacitinib Impurity 31 (CAS CATO-C4X-301831)
- Oclacitinib Impurity 32 (CAS CATO-C4X-301832)
- Oclacitinib Impurity 39 (CAS CATO-C4X-301839)
- Oclacitinib Impurity 20 (CAS 1312034-36-8)
- Oclacitinib Impurity 26 (CAS CATO-C4X-301826)
- Oclacitinib Impurity 40 (CAS CATO-C4X-301840)
- Oclacitinib impurity 1 (CAS CATO-C4X-30181)
Recommended Standards
- Valsartan Impurity 136 (CAS CATO-C4X-1057136)
- N-methyl-1-((1s,4s)-4-(methyl(7-tosyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)cyclohexyl)methanesulfonamide (CAS CATO-C4X-301833)
- 2-((3-Ethyl-4-oxo-3,4,5,6,7,8-hexahydrobenzo[4,5]thieno[2,3-d]pyrimidin-2-yl)thio)-N-(4-phenoxyphenyl)acetamide (CAS 618427-90-0)
- 3-(Cyclohexylmethyl)-5-((2,5-dimethylbenzyl)thio)-8,9-dimethoxyimidazo[1,2-c]quinazolin-2(3H)-one (CAS 1032106-83-4)
- Testosterone Decanoate EP Impurity F (CAS 59232-78-9)
- Pemafibrate Impurity 3 (CAS CATO-C4X-29033)
- Fluticasone Impurity 68 (CAS 1744-64-5)
- 2-(2-Aminopyridin-4-yl)acetic acid (CAS 887580-47-4)
- Tetraethylcopper tetrafluoroborate (CAS 15418-29-8)
- N-[2-(2,2-DImethoxy-ethyl)-phenyl]-formamide (CAS 592478-96-1)
- (2Z)-3-[(5-Chloro-2-hydroxyphenyl)amino]-2-(4-chlorophenyl)prop-2-enenitrile (CAS 338402-91-8)
- tert-Butyl 2,6-diazaspiro[3.5]nonane-6-carboxylate (CAS 885272-17-3)
- 2-(6-Bromoimidazo[1,2-a]pyridin-2-yl)acetic acid (CAS 59128-15-3)
- Semaglutide impurity 290 (CAS CATO-C4X-2226290)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com