Oclacitinib Impurity 22 CAS 1208319-34-9
| CAS No. | 1208319-34-9 |
| Molecular Formula | C22H28N4O5S2 |
| Molecular Weight | 492.61 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Oclacitinib Impurity 22 (C22H28N4O5S2) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Oclacitinib Impurity 22 (CAS 1208319-34-9) is a certified pharmaceutical impurity reference standard with the molecular formula C22H28N4O5S2 and a molecular weight of 492.61 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H28N4O5S2 |
| Molecular Weight | 492.61 g/mol |
| Purity | ≥95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 2 |
Related Oclacitinib Standards
- Oclacitinib Impurity 31 (CAS CATO-C4X-301831)
- Oclacitinib Impurity 21 (CAS 1208319-28-1)
- Oclacitinib Impurity 20 (CAS 1312034-36-8)
- Oclacitinib Impurity 32 (CAS CATO-C4X-301832)
- Oclacitinib Impurity 39 (CAS CATO-C4X-301839)
- Oclacitinib Impurity 26 (CAS CATO-C4X-301826)
- Oclacitinib Impurity 40 (CAS CATO-C4X-301840)
- Oclacitinib impurity 1 (CAS CATO-C4X-30181)
Recommended Standards
- Roxburghine A (CAS 30908-03-3)
- rel-4-[[(4R)-4,5-Dihydro-4-phenyl-2-oxazolyl]methyl]-10-[[(4S)-4,5-dihydro-4-phenyl-2-oxazolyl]methyl]-1,7-dioxa-4,10-diazacyclododecane (CAS 562841-53-6)
- Sagandipine (CAS 126294-30-2)
- Ethyl 6-amino-5-cyano-2-(((3-cyano-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-2-yl)thio)methyl)-4-(thiophen-3-yl)-4H-pyran-3-carboxylate (CAS 445384-12-3)
- Labetalol Impurity 79 (CAS CATO-C4X-246679)
- Ilaprazole impurity 187 (CAS CATO-C4X-1130187)
- Sulbactam EP Impurity F (CAS 24158-88-1)
- Ethyl 5-chloro-2-oxo-2H-chromene-3-carboxylate (CAS 70384-83-7)
- Methyl 2-(1,3-dioxo-1,3,3a,4,7,7a-hexahydro-2H-4,7-methanoisoindol-2-yl)-5-ethylthiophene-3-carboxylate (CAS 1005107-97-0)
- 3-((4-Formylphenoxy)methyl)thiophene-2-carbonitrile (CAS 256471-05-3)
- Vardenafil Oxopiperazine (Impurity) (CAS 448184-58-5)
- Methyl 2-amino-3,6-difluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate (CAS 2820536-86-3)
- 3-Bromo-4-chloro-5-fluorophenol (CAS 1805015-17-1)
- (Leu31,Pro3?)-Neuropeptide Y (porcine) trifluoroacetate salt (CAS 125580-28-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com