2-Fluorothiazol-5-amine CAS 1210907-99-5

Purity 97%+In StockPharmaceutical Standards
CAS No.1210907-99-5
Molecular FormulaC3H3FN2S
Molecular Weight118.13 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-Fluorothiazol-5-amine CAS 1210907-99-5 chemical structure

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

2-Fluorothiazol-5-amine (CAS 1210907-99-5) is a high-purity analytical reference standard with the molecular formula C3H3FN2S and a molecular weight of 118.13 g/mol.

The molecular framework of 2-Fluorothiazol-5-amine (C3H3FN2S) is characterized by a nitrile group, sulfur-containing functionality, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC3H3FN2S
Molecular Weight118.13 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)3.0
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1990
Halogen ContentF-containing
Nitrogen Atoms2
Sulfur Atoms1

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