1-(Thiophen-3-ylmethyl)-3-(2-(trifluoromethyl)phenyl)urea CAS 1211357-21-9
| CAS No. | 1211357-21-9 |
| Molecular Formula | C13H11F3N2OS |
| Molecular Weight | 300.30 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-(Thiophen-3-ylmethyl)-3-(2-(trifluoromethyl)phenyl)urea (C13H11F3N2OS) contains a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
1-(Thiophen-3-ylmethyl)-3-(2-(trifluoromethyl)phenyl)urea (CAS 1211357-21-9), molecular formula C13H11F3N2OS and molecular weight 300.30 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H11F3N2OS |
| Molecular Weight | 300.30 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
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Recommended Standards
- Ethyl 5-(3-(trifluoromethyl)phenyl)thiophene-2-carboxylate (CAS 1190235-26-7)
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- 5-(5-(Trifluoromethyl)pyridin-2-yl)-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-amine (CAS 1293290-71-7)
- (2E)-3-(5-Methylthiophen-2-yl)-1-(4-nitrophenyl)prop-2-en-1-one (CAS 1699750-47-4)
- 6-(2-Naphthyl)-6-oxohexanoic acid (CAS 132104-10-0)
- Methyl 1-methyl-2-oxocyclohexane-1-carboxylate (CAS 7500-91-6)
- 1-(4-Methylpyrimidin-2-yl)-1h-pyrazol-3-amine (CAS 1343861-23-3)
- 5-(methoxymethyl)-1,2-oxazole-3-carbaldehyde (CAS 893749-91-2)
- Linagliptin impurity 127 (CAS 1418133-47-7)
- 4,5-Bis(2-methoxyethoxy)-2-nitrobenzamide (CAS 1172625-04-5)
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- Ac-Tyr-Val-Lys-Asp-aldehyde (pseudo acid) (CAS 147821-01-0)
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