5-(5-(Trifluoromethyl)pyridin-2-yl)-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-amine CAS 1293290-71-7
| CAS No. | 1293290-71-7 |
| Molecular Formula | C12H11F3N4S |
| Molecular Weight | 300.30 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-(5-(Trifluoromethyl)pyridin-2-yl)-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-amine.
5-(5-(Trifluoromethyl)pyridin-2-yl)-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-amine (CAS 1293290-71-7), molecular formula C12H11F3N4S and molecular weight 300.30 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 5-(5-(Trifluoromethyl)pyridin-2-yl)-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-amine (C12H11F3N4S) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 300.30 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-(5-(Trifluoromethyl)pyridin-2-yl)-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H11F3N4S |
| Molecular Weight | 300.30 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Trifluoromethyl Standards
- Ethyl 5-(3-(trifluoromethyl)phenyl)thiophene-2-carboxylate (CAS 1190235-26-7)
- 2-(4-(Trifluoromethyl)phenyl)-4a,5,7,7a-tetrahydrothieno[3,4-d]pyrimidin-4(3H)-one (CAS 1956334-11-4)
- 1-(4-Methyl-2-{[2-(trifluoromethyl)phenyl]amino}-1,3-thiazol-5-yl)ethan-1-one (CAS 851450-38-9)
- 1-(4-Methyl-2-{[4-(trifluoromethyl)phenyl]amino}-1,3-thiazol-5-yl)ethan-1-one (CAS 439112-07-9)
- 6-Methyl-2-({[4-(trifluoromethyl)phenyl]methyl}sulfanyl)-3,4-dihydropyrimidin-4-one (CAS 551931-20-5)
- 1-(4-methyl-2-{[3-(trifluoromethyl)phenyl]amino}-1,3-thiazol-5-yl)ethan-1-one 932152-74-4 Z73488103 (CAS 932152-74-4)
- 4,4'-(2-(Trifluoromethyl)-1,4-phenylene)dipyridine (CAS 1429342-61-9)
- 2-[1-Methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]-5-(thiophen-2-yl)-1,3,4-oxadiazole (CAS 477762-34-8)
Recommended Standards
- N-(2,6-Difluorobenzyl)-2-(1H-indol-1-yl)acetamide (CAS 1235354-55-8)
- (R)-2-(1-Amino-4,4-dimethyl-7-nitro-1,2,3,4-tetrahydronaphthalen-1-yl)-2,2-difluoroethanol (CAS 1415108-42-7)
- 1-(Thiophen-3-ylmethyl)-3-(2-(trifluoromethyl)phenyl)urea (CAS 1211357-21-9)
- (3AR,6aR)-5-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-2,2-dimethyl-3a,6a-dihydrofuro[2,3-d][1,3]dioxol-6-yl acetate (CAS 14686-88-5)
- 1,3,4-Thiadiazole-2-carbonitrile (CAS 1121585-02-1)
- (6-Isopropoxypyridazin-3-yl)methanol (CAS 1250193-45-3)
- 2-(Furan-3-yl)-1H-pyrrole (CAS 72078-44-5)
- 2-(2-Fluorobenzenesulfonyl)-1-phenylethan-1-one (CAS 1378441-13-4)
- 1-Ethynyl-2-methylcyclohexan-1-ol (CAS 15564-30-4)
- 4-N-benzylquinazoline-2,4-diamine (CAS 258514-31-7)
- 1-(2-Methyl-6-phenylpyrimidin-4-yl)ethanone (CAS 64571-46-6)
- 6-Oxa-2-azaspiro[3.4]octane oxalate(2:1) (CAS 1523571-05-2)
- (4E)-3-(Chloromethyl)-4-[(2-chloropyridin-3-yl)-methylene]isoxazol-5(4H)-one 1142199-87-8 9247AC C10H6Cl2N2O2 (CAS 1142199-87-8)
- C-Peptide（dog） (CAS 39016-05-2)
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