2-(chloromethyl)-6-(difluoromethyl)pyridine CAS 1211525-99-3
| CAS No. | 1211525-99-3 |
| Molecular Formula | C7H12ClF2N |
| Molecular Weight | 183.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-(chloromethyl)-6-(difluoromethyl)pyridine is closely related to fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 2-(chloromethyl)-6-(difluoromethyl)pyridine (CAS 1211525-99-3), a certified reference material (molecular formula C7H12ClF2N, MW 183.63 g/mol) for analytical method development and quality control.
Owing to fluorine/chlorine substitution, 2-(chloromethyl)-6-(difluoromethyl)pyridine is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 183.63 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-(chloromethyl)-6-(difluoromethyl)pyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H12ClF2N |
| Molecular Weight | 183.63 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related chloromethyl Standards
- 3-(Chloromethyl)-N-methylbenzamide (CAS 123944-75-2)
- 1-(2-(Chloromethyl)-6-methylpyridin-4-yl)ethan-1-one (CAS 1393584-71-8)
- 4-(chloromethyl)-N-methylbenzamide (CAS 220875-88-7)
- N-(2-(Chloromethyl)phenyl)acetamide (CAS 90562-37-1)
- n-[3-(chloromethyl)phenyl]acetamide (CAS 90942-40-8)
- 4'-(Chloromethyl)acetanilide 4-Acetamidobenzyl chloride 4-Acetylaminobenzyl chloride 54777-65-0 N-[p-(Chloromethyl)phenyl]acetamide n-[4-(chloromethyl)phenyl]acetamide (CAS 54777-65-0)
- 5-(Chloromethyl)pyrazolo[1,5-a]pyrimidin-7(4H)-one (CAS 1258651-02-3)
- 5-(Chloromethyl)benzo[d]thiazole (CAS 1262889-04-2)
Recommended Standards
- 5-Chloro-2-isopropylnicotinaldehyde (CAS 1211515-26-2)
- (S)-7-chlorochroman-4-amine (CAS 1213320-82-1)
- 1-(6-Chloro-4-methylpyridin-3-yl)propan-1-one (CAS 1207260-06-7)
- 6-Chloro-1,2,3,4-tetrahydroisoquinolin-4-ol (CAS 1216281-89-8)
- 3-Ethyl-4-methyl-1H-pyrazole (CAS 7231-33-6)
- Methyl 2-((4-aminophenyl)thio)propanoate (CAS 1251301-50-4)
- Cyclopropyl(piperidin-4-yl)methanone (CAS 1332455-35-2)
- 2-Bromo-1-(2-((2-(pyridin-2-yl)ethyl)amino)-1H-imidazol-4-yl)ethanone (CAS 88723-60-8)
- 2'-Amino-5'-cyano-[1,1':3',1''-terphenyl]-4,4''-dicarboxylic acid (CAS 2378180-01-7)
- 7,8-Difluoro-1,2,3,4-tetrahydroquinoline (CAS 1249025-43-1)
- 6-(Aminomethyl)-5-fluoropyridin-3-ol (CAS 1337881-00-1)
- 1-(Piperidin-1-ylmethyl)-1H-benzo[d][1,2,3]triazole (CAS 15622-20-5)
- 5-Amino-1-(3-(methylsulfonyl)propyl)pyridin-2(1h)-one (CAS 1178431-19-0)
- Liraglutide Impurity 13 TFA Salt (CAS CATO-C4X-199213)
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