5-(1,1-Difluoroethyl)pyridin-3-amine CAS 1211540-26-9
| CAS No. | 1211540-26-9 |
| Molecular Formula | C7H8F2N2 |
| Molecular Weight | 158.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-(1,1-Difluoroethyl)pyridin-3-amine.
5-(1,1-Difluoroethyl)pyridin-3-amine (CAS 1211540-26-9), molecular formula C7H8F2N2 and molecular weight 158.15 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 5-(1,1-Difluoroethyl)pyridin-3-amine (C7H8F2N2) is characterized by a nitrile group, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 5-(1,1-Difluoroethyl)pyridin-3-amine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H8F2N2 |
| Molecular Weight | 158.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Difluoroethyl Standards
- 2-(1,1-Difluoroethyl)-3-methylpyrazine (CAS 1171916-84-9)
- 6-(1,1-Difluoroethyl)pyridin-2-amine (CAS 1211515-86-4)
- 5-(1,1-Difluoroethyl)pyridin-2-amine (CAS 1335054-32-4)
- 4-(1,1-Difluoroethyl)pyridin-2-amine (CAS 1522240-28-3)
- 2-(1,1-Difluoroethyl)phenol (CAS 1547144-39-7)
- 4-(1,1-Difluoroethyl)phenol (CAS 1552636-45-9)
- 3-(1,1-Difluoroethyl)phenol (CAS 1554368-89-6)
- 4-(2,2-Difluoroethyl)phenol (CAS 1784794-52-0)
Recommended Standards
- (6-(Difluoromethyl)pyridin-3-yl)methanamine (CAS 1211534-72-3)
- (2-(Difluoromethyl)pyridin-4-yl)methanamine (CAS 1211589-22-8)
- 2,3-Difluorophenetole (CAS 121219-07-6)
- 2-Methyl-3,4-difluoroanisole (CAS 1208078-30-1)
- N-allyl-2-bromo-N-phenylpropanamide (CAS 307346-20-9)
- 3-(1-Hydrazinylethyl)pyridine (CAS 1016681-07-4)
- 2-Hydroxy-2-methyl-3-(4-methylbenzenesulfonyl)-N-[3-(trifluoromethyl)phenyl]propanamide (CAS 338424-47-8)
- (2S)-1-[(pyridin-2-yl)carbonyl]pyrrolidine-2-carboxylic acid (CAS 167868-25-9)
- Ethyl 2-(4-methoxyphenyl)-5-methylthiazole-4-carboxylate (CAS 115299-15-5)
- 11-Amino-5,6,7,8,9,10-hexahydro-2-hydroxy-6,9-methanobenzocyclooctene (CAS 82838-31-1)
- H-Tyr-OMe · HCl (CAS 3417-91-2)
- Silybin B-d3 (CAS 142797-34-0 (Non-labelled))
- 6,7,8,9-Tetrahydrothiazolo[4,5-h]isoquinolin-2-amine (CAS 120546-68-1)
- Des-Ser34-Gly33Tirzepatide (CAS CATO-CPTD788941)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
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