5-Bromo-2-chloro-4-fluoropyridine CAS 1211580-49-2
| CAS No. | 1211580-49-2 |
| Molecular Formula | C5H2BrClFN |
| Molecular Weight | 210.43 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 5-Bromo-2-chloro-4-fluoropyridine is closely related to a nitrile group, fluorine/chlorine/bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 5-Bromo-2-chloro-4-fluoropyridine (CAS 1211580-49-2), a certified reference material (molecular formula C5H2BrClFN, MW 210.43 g/mol) for analytical method development and quality control.
The molecular framework of 5-Bromo-2-chloro-4-fluoropyridine (C5H2BrClFN) is characterized by a nitrile group, fluorine/chlorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-Bromo-2-chloro-4-fluoropyridine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C5H2BrClFN |
| Molecular Weight | 210.43 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl/Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
- 4-Bromo-3-chloro-2-fluoropyridine (CAS 1017793-21-3)
- 2-Bromo-4-chloro-5-fluoropyridine (CAS 1033203-44-9)
- 2-Bromo-5-chloro-4-fluoropyridine (CAS 1033203-45-0)
- 5-Bromo-4-chloro-2-fluoropyridine (CAS 1184920-15-7)
- 2-Bromo-3-chloro-6-fluoropyridine (CAS 1211515-01-3)
- 2-Bromo-6-chloro-3-fluoropyridine (CAS 1211515-03-5)
- 4-Bromo-2-chloro-3-fluoropyridine (CAS 1211526-56-5)
- 3-Bromo-4-chloro-2-fluoropyridine (CAS 1211528-25-4)
Recommended Standards
- 3-Bromo-2-chloro-6-fluoropyridine (CAS 1211578-75-4)
- 4-Bromo-5-chloro-2-fluoropyridine (CAS 1211580-71-0)
- 6-Bromo-3-chloro-2-fluoropyridine (CAS 1211578-30-1)
- 4-Bromo-3-chloro-5-fluoropyridine (CAS 1211590-18-9)
- 6-Hydroxy-3H-imidazo[4,5-b]pyridine-7-carboxylic acid (CAS 1820665-54-0)
- (2-Bromo-5-iodo-3-methylphenyl)methanol (CAS 2091676-26-3)
- Emodin-8-glucoside (CAS 23313-21-5)
- 5-(Bromomethyl)-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-tetrazole (CAS 2578785-78-9)
- 2-Chloro-1-methylpyridinium Iodide (CAS 14338-32-0)
- 5-Chloro-1H-pyrazolo[3,4-c]pyridine (CAS 76006-08-1)
- 2-Bromo-8-chloro-[1,2,4]triazolo[1,5-a]pyrazine (CAS 1936016-69-1)
- 5-Amino-3-methyl-thiophene-2,4-dicarboxylic acid -4-ethyl ester 2-methyl ester (CAS 30823-51-9)
- 4-({Prop-2-yn-1-yl)-3,4-dihydrothieno[3,2-f][1,4]thiazepin-5(2H)-one (CAS 477845-64-0)
- Peptide 6A (H-6905.0005) (CAS 73549-32-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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