3-Bromo-4-chloro-2-fluoropyridine CAS 1211528-25-4
| CAS No. | 1211528-25-4 |
| Molecular Formula | C5H2BrClFN |
| Molecular Weight | 210.43 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-Bromo-4-chloro-2-fluoropyridine is closely related to a nitrile group, fluorine/chlorine/bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
3-Bromo-4-chloro-2-fluoropyridine (CAS 1211528-25-4) is a high-purity analytical reference standard with the molecular formula C5H2BrClFN and a molecular weight of 210.43 g/mol.
Structurally, 3-Bromo-4-chloro-2-fluoropyridine (C5H2BrClFN) contains a nitrile group, fluorine/chlorine/bromine substitution. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 210.43 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C5H2BrClFN |
| Molecular Weight | 210.43 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl/Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
- 4-Bromo-3-chloro-2-fluoropyridine (CAS 1017793-21-3)
- 2-Bromo-4-chloro-5-fluoropyridine (CAS 1033203-44-9)
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