Ethyl 4,4,4-trifluoro-3-(methylamino)but-2-enoate CAS 121303-76-2

Purity 97%+In StockPharmaceutical Standards
CAS No.121303-76-2
Molecular FormulaC7H10F3NO2
Molecular Weight197.16 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

Ethyl 4,4,4-trifluoro-3-(methylamino)but-2-enoate CAS 121303-76-2 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 197.16 g/mol gives Ethyl 4,4,4-trifluoro-3-(methylamino)but-2-enoate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Ethyl 4,4,4-trifluoro-3-(methylamino)but-2-enoate (CAS 121303-76-2), molecular formula C7H10F3NO2 and molecular weight 197.16 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of Ethyl 4,4,4-trifluoro-3-(methylamino)but-2-enoate (C7H10F3NO2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC7H10F3NO2
Molecular Weight197.16 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityLight-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)2.0
CAS Registry Year (est.)1991
Halogen ContentF-containing
Nitrogen Atoms1

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