5-(Difluoromethyl)-1-methyl-1,2-dihydro-3H-pyrazol-3-one CAS 121303-75-1
| CAS No. | 121303-75-1 |
| Molecular Formula | C5H6F2N2O |
| Molecular Weight | 148.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 5-(Difluoromethyl)-1-methyl-1,2-dihydro-3H-pyrazol-3-one (CAS 121303-75-1), a certified reference material (molecular formula C5H6F2N2O, MW 148.11 g/mol) for analytical method development and quality control.
Owing to an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 5-(Difluoromethyl)-1-methyl-1,2-dihydro-3H-pyrazol-3-one is typically white to pale yellow liquid. Its solid-state physicochemical attributes — including a molecular weight of 148.11 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-(Difluoromethyl)-1-methyl-1,2-dihydro-3H-pyrazol-3-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C5H6F2N2O |
| Molecular Weight | 148.11 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Difluoromethyl Standards
- 3-(Difluoromethyl)-1-methyl-1H-pyrazol-5(4H)-one (CAS 1048018-91-2)
- [1-(difluoromethyl)-1H-pyrazol-5-yl]methanol (CAS 1245772-28-4)
- (1-(Difluoromethyl)-1H-pyrazol-3-yl)methanol (CAS 1245772-78-4)
- 3-(Difluoromethyl)-1-methyl-1H-pyrazol-5-ol (CAS 129922-58-3)
- (5-(Difluoromethyl)furan-2-yl)methanol (CAS 152932-54-2)
- 5-(Difluoromethyl)-1-methyl-1H-1,2,4-triazol-3-amine (CAS 1785198-29-9)
- [5-(Difluoromethyl)-1,2-oxazol-3-yl]methanamine (CAS 1896928-61-2)
- (3-(Difluoromethyl)-1H-pyrazol-4-yl)methanol (CAS 2254338-42-4)
Recommended Standards
- 3-(1,1-difluoroethyl)-1,2-oxazol-5-amine (CAS 1188909-17-2)
- L-Lyxono-1,4-lactone (CAS 104196-15-8)
- Ethyl 4,4-difluorobut-2-ynoate (CAS 129922-56-1)
- sodium 2-cyano-3-formamidoprop-1-en-1-olate (CAS 106030-08-4)
- N-Methyl-1-(5-methyl-1H-benzimidazol-2-yl)methanamine dihydrochloride (CAS 1158445-87-4)
- 2-((3-(Trifluoromethyl)phenyl)amino)thiazole-4-carbaldehyde (CAS 126533-84-4)
- N-(4-(Benzo[d]thiazol-2-yl)phenyl)-9H-purin-6-amine (CAS 920519-48-8)
- N-Acetyl-b-alanine (CAS 3025-95-4)
- Imipenem impurity 33 (CAS CATO-C4X-1662133)
- (2S,4R)-2-Amino-4-hydroxypentanoic acid (CAS 21704-88-1)
- (R)-9-Chloro-5-ethyl-5-hydroxy-10-methyl-12-((4-methylpiperidin-1-yl)methyl)-4,5-dihydrooxepino[3',4':6,7]indolizino[1,2-b]quinoline-3,15(1H,13H)-dione hydrochloride (CAS 220997-99-9)
- N-Me-L-Val-Ome.Hcl (CAS 339-44-4)
- 2-((2,4-dimethylphenyl)amino)benzoic acid (CAS 27210-58-8)
- Tirzepatide Impurity 51 (CAS CATO-C4X-324051)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com