6-(Trifluoromethyl)pyridine-2-thiol CAS 121307-80-0
| CAS No. | 121307-80-0 |
| Molecular Formula | C6H4F3NS |
| Molecular Weight | 179.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
6-(Trifluoromethyl)pyridine-2-thiol (CAS 121307-80-0), molecular formula C6H4F3NS and molecular weight 179.16 g/mol, is a CATO reference standard with documented purity and traceability.
6-(Trifluoromethyl)pyridine-2-thiol (C6H4F3NS) contains a nitrile group, sulfur-containing functionality, fluorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 6-(Trifluoromethyl)pyridine-2-thiol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H4F3NS |
| Molecular Weight | 179.16 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Trifluoromethyl Standards
- 2-(Trifluoromethyl)pyridine-4-thiol (CAS 1093954-03-0)
- 2-(Trifluoromethyl)pyridine-3-thiol (CAS 1801693-48-0)
- 3-(Trifluoromethyl)pyridine-4-thiol (CAS 1806316-97-1)
- 2-[(trifluoromethyl)sulfanyl]pyridine (CAS 57830-49-6)
- 3-((Trifluoromethyl)thio)pyridine (CAS 58313-26-1)
- 5-(Trifluoromethyl)pyridine-2(1H)-thione (CAS 76041-72-0)
- 5-(Trifluoromethyl)pyridine-3-thiol (CAS 912545-82-5)
- 6-(Trifluoromethyl)pyridine-3-thiol (CAS 677772-36-0)
Recommended Standards
- 1-(2,2-Difluoroethyl)pyrrolidine-2-carboxylic acid (CAS 1162114-85-3)
- 2-(3,3-Difluoropiperidin-1-yl)acetic acid (CAS 1240018-55-6)
- 1-Amino-4,4-difluorocyclohexanecarboxylic acid (CAS 1240529-10-5)
- 2,2-difluoro-2-(pyridin-2-yl)acetic acid (CAS 1039621-73-2)
- 7-oxaspiro[3.5]nonan-6-one (CAS 518284-70-3)
- N-propyl-3,4-dihydroisoquinoline-2(1H)-carboxamide (CAS 88630-43-7)
- 2-Amino-6-bromo-4-methylbenzonitrile (CAS 2385515-63-7)
- 2-(3-Methoxyphenyl)ethylisocyanide (CAS 602269-00-1)
- Dolutegravir Impurity 67 (CAS CATO-C4X-162067)
- 9-tert-butoxy-9-oxo-nonanoic acid (CAS 1290540-34-9)
- 2165-21-1 1H-Tetrazole-1,5-diamine DTXSID80308652 (CAS 2165-21-1)
- 1-Benzyl-3-(1-phenylethyl)urea (CAS 98672-63-0)
- 1,4-Dichloro-2-fluoro-5-nitrobenzene (CAS 2624-66-0)
- Galanin-Like Peptide (rat) trifluoroacetate salt (CAS 245114-97-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com