5-(4-Fluorophenyl)-3-(trifluoromethyl)pyridine-2-thiol CAS 1214340-84-7
| CAS No. | 1214340-84-7 |
| Molecular Formula | C12H7F4NS |
| Molecular Weight | 273.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 5-(4-Fluorophenyl)-3-(trifluoromethyl)pyridine-2-thiol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies 5-(4-Fluorophenyl)-3-(trifluoromethyl)pyridine-2-thiol (CAS 1214340-84-7), a certified reference material (molecular formula C12H7F4NS, MW 273.25 g/mol) for analytical method development and quality control.
The molecular framework of 5-(4-Fluorophenyl)-3-(trifluoromethyl)pyridine-2-thiol (C12H7F4NS) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C12H7F4NS |
| Molecular Weight | 273.25 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Fluorophenyl Standards
- 3-(2-Fluorophenyl)-5-(trifluoromethyl)pyridine-2-thiol (CAS 1214324-45-4)
- 5-(2-Fluorophenyl)-6-(trifluoromethyl)pyridine-2-thiol (CAS 1214333-23-9)
- 5-(3-Fluorophenyl)-3-(trifluoromethyl)pyridine-2-thiol (CAS 1214340-79-0)
- 5-(4-Fluorophenyl)-6-(trifluoromethyl)pyridine-2-thiol (CAS 1214342-69-4)
- 3-(4-Fluorophenyl)-5-(trifluoromethyl)pyridine-2-thiol (CAS 1214346-80-1)
- 3-(4-Fluorophenyl)-6-(trifluoromethyl)pyridine-2-thiol (CAS 1214349-14-0)
- 3-(2-Fluorophenyl)-6-(trifluoromethyl)pyridine-2-thiol (CAS 1214349-46-8)
- 5-(2-Fluorophenyl)-3-(trifluoromethyl)pyridine-2-thiol (CAS 1214353-96-4)
Recommended Standards
- Methyl(3S,4R)-4-(4-(trifluoromethyl)phenyl)pyrrolidine-3-carboxylate (CAS 1212257-11-8)
- 1-Benzyl-4-(trifluoromethyl)pyrrolidine-3-carboxylic acid (CAS 1210383-94-0)
- 1-(4-(1h-Tetrazol-1-yl)phenyl)-5-oxopyrrolidine-3-carboxylic acid (CAS 1203055-11-1)
- 5-(3-Fluorophenyl)-6-(trifluoromethyl)pyridine-2-thiol (CAS 1214356-38-3)
- N-[(4-Fluorophenyl)methyl]-1H,2H-naphtho[2,1-b]furan-2-carboxamide (CAS 478064-62-9)
- N-Propyl-3-(trifluoromethoxy)aniline (CAS 1020966-73-7)
- Mepronil (CAS 55814-41-0)
- 3-methoxy-2,2,4-trimethylcyclobutan-1-one (CAS 1427378-92-4)
- 1,2,2,6,6-Pentamethylpiperidin-4-one (CAS 5554-54-1)
- 4-{[(1E)-2-cyano-2-(thiophen-3-yl)eth-1-en-1-yl]amino}benzoic acid (CAS 477851-25-5)
- 1-(2,5-Dichlorobenzoyl)pyrrolidine-2-carboxylic acid (CAS 1101837-02-8)
- 4-(4-(4-Fluorophenyl)-2-(4-(methylsulfonyl)phenyl)-1H-imidazol-5-yl)pyridine (CAS 152121-46-5)
- 1-(1H-Benzo[d]imidazol-2-yl)propan-2-one oxalate (CAS 6961-13-3)
- Semaglutide Impurity 187 (CAS CATO-C4X-2226187)
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