5-(3-Fluorophenyl)-6-(trifluoromethyl)pyridine-2-thiol CAS 1214356-38-3

Purity 97%+In StockPharmaceutical Standards
CAS No.1214356-38-3
Molecular FormulaC12H7F4NS
Molecular Weight273.25 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

5-(3-Fluorophenyl)-6-(trifluoromethyl)pyridine-2-thiol CAS 1214356-38-3 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 273.25 g/mol gives 5-(3-Fluorophenyl)-6-(trifluoromethyl)pyridine-2-thiol distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies 5-(3-Fluorophenyl)-6-(trifluoromethyl)pyridine-2-thiol (CAS 1214356-38-3), a certified reference material (molecular formula C12H7F4NS, MW 273.25 g/mol) for analytical method development and quality control.

Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine substitution, 5-(3-Fluorophenyl)-6-(trifluoromethyl)pyridine-2-thiol is typically pale yellow to yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 273.25 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC12H7F4NS
Molecular Weight273.25 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1990
Halogen ContentF-containing
Nitrogen Atoms1
Sulfur Atoms1

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