3-Chloro-5-fluoropyridin-2(1H)-one CAS 1214345-43-3

Description

Compared with other compounds in its class, the molecular weight of 147.53 g/mol gives 3-Chloro-5-fluoropyridin-2(1H)-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies 3-Chloro-5-fluoropyridin-2(1H)-one (CAS 1214345-43-3), a certified reference material (molecular formula C5H3ClFNO, MW 147.53 g/mol) for analytical method development and quality control.

The molecular framework of 3-Chloro-5-fluoropyridin-2(1H)-one (C5H3ClFNO) is characterized by an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 3-Chloro-5-fluoropyridin-2(1H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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