5-Chloro-2-fluoropyridin-4-ol CAS 1227571-47-2
| CAS No. | 1227571-47-2 |
| Molecular Formula | C5H3ClFNO |
| Molecular Weight | 147.53 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 147.53 g/mol gives 5-Chloro-2-fluoropyridin-4-ol distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
5-Chloro-2-fluoropyridin-4-ol (CAS 1227571-47-2), molecular formula C5H3ClFNO and molecular weight 147.53 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 5-Chloro-2-fluoropyridin-4-ol (C5H3ClFNO) is characterized by an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 5-Chloro-2-fluoropyridin-4-ol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C5H3ClFNO |
| Molecular Weight | 147.53 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 5-Chloro-2-fluoropyridin-3-ol (CAS 1003711-65-6)
- 2-Chloro-3-fluoro-4-hydroxypyridine (CAS 1184172-46-0)
- 2-Chloro-5-fluoropyridin-4-ol (CAS 1196153-96-4)
- 6-Chloro-4-fluoropyridin-3-ol (CAS 1211530-63-0)
- 3-Chloro-5-fluoro-4-hydroxypyridine (CAS 1214327-70-4)
- 3-Chloro-5-fluoropyridin-2(1H)-one (CAS 1214345-43-3)
- 3-Chloro-5-fluoropyridine 1-oxide (CAS 1221793-68-5)
- 3-Chloro-2-fluoropyridin-4-ol (CAS 1227499-28-6)
Recommended Standards
- 4-Chloro-5-fluoropyridin-2(1H)-one (CAS 1227571-38-1)
- 5-Chloro-4-fluoropyridin-2-ol (CAS 1227571-77-8)
- 2-chloro-4-fluoropyridin-3-ol (CAS 1227577-96-9)
- 4-chloro-6-fluoropyridin-3-ol (CAS 1227578-00-8)
- 7-Hydroxy-2-methylpyrazolo[1,5-a]pyrimidin-5(4H)-one (CAS 754210-99-6)
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Why CATO?
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