5-(Difluoromethyl)-2-fluorophenol CAS 1214348-52-3
| CAS No. | 1214348-52-3 |
| Molecular Formula | C7H5F3O |
| Molecular Weight | 162.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-(Difluoromethyl)-2-fluorophenol (CAS 1214348-52-3), molecular formula C7H5F3O and molecular weight 162.11 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system, 5-(Difluoromethyl)-2-fluorophenol is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 162.11 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 5-(Difluoromethyl)-2-fluorophenol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H5F3O |
| Molecular Weight | 162.11 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
Related Difluoromethyl Standards
- 2-(Difluoromethyl)-4-fluorophenol (CAS 1214326-61-0)
- 2-(Difluoromethyl)-3-fluorophenol (CAS 1214333-85-3)
- 4-(Difluoromethyl)-2-fluorophenol (CAS 1214333-89-7)
- 3-(Difluoromethyl)-5-fluorophenol (CAS 1214333-96-6)
- 3-(Difluoromethyl)-4-fluorophenol (CAS 1214352-39-2)
- 2-(Difluoromethyl)-5-fluorophenol (CAS 1214367-26-6)
- 3-(Difluoromethyl)-2-fluorophenol (CAS 1214379-67-5)
- 4-(Difluoromethyl)-3-fluorophenol (CAS 1214383-40-0)
Recommended Standards
- (2,3,4-Trifluorophenyl)hydrazine (CAS 119452-62-9)
- 2-(Difluoromethyl)-6-fluorophenol (CAS 1214388-76-7)
- (2,4,6-Trifluorophenyl)methanol (CAS 118289-07-9)
- 4-(Difluoromethyl)-5-fluoropyridin-2-amine (CAS 1219013-97-4)
- N-Chlorobenzenesulfonamide (CAS 80-16-0)
- 1-(2-((5-Amino-4-((2-(dimethylamino)ethyl)(methyl)amino)-2-methoxyphenyl)amino)pyrimidin-4-yl)-5-fluoro-3-methyl-1,3-dihydro-2H-benzo[d]imidazol-2-one (CAS 2050908-12-6)
- 3-(Pyridin-2-yl)prop-2-yn-1-amine (CAS 794496-99-4)
- (3-Bromophenyl)(3-fluoro-5-methylphenyl)methanone (CAS 951886-67-2)
- N1-(furan-2-ylmethyl)-N1-methylethane-1,2-diamine (CAS 741290-33-5)
- 3-(aminomethyl)-N-(pyridin-4-yl)benzamide dihydrochloride (CAS 173897-43-3)
- 5-(2-Fluoropropan-2-yl)isoxazol-3-amine (CAS 1188908-86-2)
- Gizzerosine (CAS 89238-78-8)
- 4-(Methyl(phenyl)amino)-2H-pyrido[1,2-a]pyrimidin-2-one (CAS 111680-65-0)
- (Des-His1,Glu?)-Glucagon (1-29) amide (human, rat, porcine) (CAS 110084-95-2)
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