4-(difluoromethoxy)-3-nitropyridine CAS 1214360-74-3
| CAS No. | 1214360-74-3 |
| Molecular Formula | C6H4F2N2O3 |
| Molecular Weight | 190.10 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 4-(difluoromethoxy)-3-nitropyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
4-(difluoromethoxy)-3-nitropyridine (CAS 1214360-74-3) is a high-purity analytical reference standard with the molecular formula C6H4F2N2O3 and a molecular weight of 190.10 g/mol.
Based on its molecular formula C6H4F2N2O3, 4-(difluoromethoxy)-3-nitropyridine contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 190.10 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H4F2N2O3 |
| Molecular Weight | 190.10 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related difluoromethoxy Standards
- 3-(Difluoromethoxy)-2-nitropyridine (CAS 1111637-77-4)
- 2-(Difluoromethoxy)-5-nitropyridine (CAS 1192813-41-4)
- 2-(Difluoromethoxy)-3-nitropyridine (CAS 1214341-49-7)
- 2-(Difluoromethoxy)pyrazine-6-carboxylic acid (CAS 1261630-46-9)
- 2-(Difluoromethoxy)-5-fluorobenzaldehyde (CAS 1214326-36-9)
- 2-(Difluoromethoxy)-4-fluorobenzaldehyde (CAS 1214333-04-6)
- 2-(Difluoromethoxy)-6-fluorobenzaldehyde (CAS 1214333-68-2)
- 2-(Difluoromethoxy)-3-fluorobenzaldehyde (CAS 1214337-22-0)
Recommended Standards
- 4-(difluoromethyl)-2-hydroxy-pyrimidine-5-carboxylic acid (CAS 1260902-01-9)
- 5-Fluoro-4-(trifluoromethyl)picolinonitrile (CAS 1156542-31-2)
- 4,5,6,7-Tetrafluoro-1H-indazole (CAS 1294396-96-5)
- 5-Fluoro-3-(trifluoromethyl)picolinonitrile (CAS 1421313-95-2)
- (R)-tert-Butyl 3-(2-chloronicotinamido)pyrrolidine-1-carboxylate (CAS 1354018-47-5)
- 4-amino-3,5-difluorobenzene-1-carboximidamide hydrochloride (CAS 1803597-06-9)
- 654663-85-1 9063AF Acantrifoic acid A C32H48O7 (CAS 654663-85-1)
- Clomiphene Impurity 9 (CAS 14770-94-6)
- (E)-Methoxy(1-{6-methyl-[1,2,4]triazolo[3,2-b][1,3]thiazol-5-yl}-2-[(4-methylphenyl)sulfanyl]ethylidene)amine (CAS 866049-36-7)
- 4-Chloro-N-[6-(trifluoromethyl)-[1,3]thiazolo[4,5-b]pyridin-2-yl]benzamide (CAS 1354448-65-9)
- 2-(2-methyl-4-nitrophenyl)acetonitrile (CAS 543683-45-0)
- 3-(2-(1H-pyrrol-1-yl)phenoxy)butan-2-one (CAS 339014-73-2)
- N-Cyclohexyl-p-toluenesulfonamide (CAS 80-30-8)
- Thymopoietin II Peptide Fragment (CAS 56795-64-3)
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