4-(difluoromethyl)-2-hydroxy-pyrimidine-5-carboxylic acid CAS 1260902-01-9

Purity 97%+In StockPharmaceutical Standards
CAS No.1260902-01-9
Molecular FormulaC6H4F2N2O3
Molecular Weight190.10 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-(difluoromethyl)-2-hydroxy-pyrimidine-5-carboxylic acid CAS 1260902-01-9 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 190.10 g/mol gives 4-(difluoromethyl)-2-hydroxy-pyrimidine-5-carboxylic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

4-(difluoromethyl)-2-hydroxy-pyrimidine-5-carboxylic acid (CAS 1260902-01-9) is a high-purity analytical reference standard with the molecular formula C6H4F2N2O3 and a molecular weight of 190.10 g/mol.

Based on its molecular formula C6H4F2N2O3, 4-(difluoromethyl)-2-hydroxy-pyrimidine-5-carboxylic acid contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 190.10 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 4-(difluoromethyl)-2-hydroxy-pyrimidine-5-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC6H4F2N2O3
Molecular Weight190.10 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, ethanol, DMSO, water
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1990
Halogen ContentF-containing
Nitrogen Atoms2

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