6-(Trifluoromethyl)-[1,1'-biphenyl]-3-sulfonyl chloride CAS 1214366-01-4

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6-(Trifluoromethyl)-[1,1'-biphenyl]-3-sulfonyl chloride.

6-(Trifluoromethyl)-[1,1'-biphenyl]-3-sulfonyl chloride (CAS 1214366-01-4), molecular formula C13H8ClF3O2S and molecular weight 320.71 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 6-(Trifluoromethyl)-[1,1'-biphenyl]-3-sulfonyl chloride (C13H8ClF3O2S) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 6-(Trifluoromethyl)-[1,1'-biphenyl]-3-sulfonyl chloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

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