tert-Butyl 2-chloro-5-fluorobenzoate CAS 1215206-26-0
| CAS No. | 1215206-26-0 |
| Molecular Formula | C11H12ClFO2 |
| Molecular Weight | 230.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of tert-Butyl 2-chloro-5-fluorobenzoate (C11H12ClFO2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
tert-Butyl 2-chloro-5-fluorobenzoate (CAS 1215206-26-0), molecular formula C11H12ClFO2 and molecular weight 230.66 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures tert-Butyl 2-chloro-5-fluorobenzoate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H12ClFO2 |
| Molecular Weight | 230.66 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
Recommended Standards
- Ethyl 3-(2-chloro-6-fluorophenyl)propanoate (CAS 1057674-03-9)
- 3-(2-Chloro-6-fluorophenyl)-2,2-dimethylpropanoic acid (CAS 1225542-55-1)
- tert-Butyl 3-chloro-2-fluorobenzoate (CAS 1055975-14-8)
- Tert-butyl 2-chloro-6-fluorobenzoate (CAS 1410564-70-3)
- Tetrabutylammonium hydrogen sulfite (CAS 87742-13-0)
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- Semaglutide Impurity 158 (x TFA Salt) (CAS CATO-C4X-2226158)
Why CATO?
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