2-Chloro-4-propionamidobenzamide CAS 1215376-75-2
| CAS No. | 1215376-75-2 |
| Molecular Formula | C10H11ClN2O2 |
| Molecular Weight | 226.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
2-Chloro-4-propionamidobenzamide (CAS 1215376-75-2) is a high-purity analytical reference standard with the molecular formula C10H11ClN2O2 and a molecular weight of 226.66 g/mol.
The molecular framework of 2-Chloro-4-propionamidobenzamide (C10H11ClN2O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 2-Chloro-4-propionamidobenzamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H11ClN2O2 |
| Molecular Weight | 226.66 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 5-Chloro-6-(pyrrolidin-1-yl)nicotinic acid (CAS 1019127-02-6)
- 2-chloro-6-(cyclopropylmethoxy)benzoic acid (CAS 1020934-87-5)
- (3-Chloro-5-methoxy-4-(prop-2-yn-1-yloxy)phenyl)methanol (CAS 1030765-35-5)
- 1-(5-Chloro-2-methoxyphenyl)cyclopropane-1-carboxylic acid (CAS 1039952-36-7)
- Ethyl 4-chloro-2-cyclopropylpyrimidine-5-carboxylate (CAS 1044770-40-2)
- Benzyl 2-chloro-3-oxobutanoate (CAS 104517-65-9)
- 2-(4-Chloro-2-nitrophenyl)pyrrolidine (CAS 1092291-34-3)
- 1-(2-Chloro-phenyl)-2-(1,3-dioxolan-2-yl)-ethanone (CAS 110251-20-2)
Recommended Standards
- (S)-2-(4-chloro-3-nitrophenyl)pyrrolidine (CAS 1213926-62-5)
- (2-Chloro-3-pyridinyl)(3-hydroxy-1-pyrrolidinyl)-methanone (CAS 1219981-43-7)
- (S)-2-(2-chloro-5-nitrophenyl)pyrrolidine (CAS 1213589-15-1)
- N'-(1-(2-Chlorophenyl)ethylidene)-2-hydroxyacetohydrazide (CAS 122432-93-3)
- Ethyl 3-amino-3-phenylpropanoate (CAS 6335-76-8)
- alpha-(Trifluoromethyl)-DL-phenylalanine, N-CBZ protected (CAS 139520-45-9)
- Chromoionophore IV (CAS 124522-01-6)
- 3-Phenoxyphenyl morpholine-4-carboxylate (CAS 712345-27-2)
- (2S,4S)-1-(tert-butoxycarbonyl)-4-(thiophen-2-ylmethyl)pyrrolidine-2-carboxylic acid (CAS 959575-44-1)
- N-(4-Dodecanamidophenyl)nicotinamide (CAS 337935-65-6)
- 4-(2-Methoxyphenyl)-1-phenyl-1H-pyrazolo[3,4-d]pyrimidine (CAS 87412-75-7)
- N-(5-Amino-1,3,4-thiadiazol-2-yl)benzamide (CAS 28863-43-6)
- 1'-(4-Propoxyphenyl)-[1,3'-bipyrrolidine]-2',5'-dione (CAS 89143-17-9)
- Semaglutide Impurity 15 (CAS CATO-C4X-222615)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com