alpha-(Trifluoromethyl)-DL-phenylalanine, N-CBZ protected CAS 139520-45-9
| CAS No. | 139520-45-9 |
| Molecular Formula | C18H16F3NO4 |
| Molecular Weight | 367.32 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 367.32 g/mol gives alpha-(Trifluoromethyl)-DL-phenylalanine, N-CBZ protected distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies alpha-(Trifluoromethyl)-DL-phenylalanine, N-CBZ protected (CAS 139520-45-9), a certified reference material (molecular formula C18H16F3NO4, MW 367.32 g/mol) for analytical method development and quality control.
alpha-(Trifluoromethyl)-DL-phenylalanine, N-CBZ protected (C18H16F3NO4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H16F3NO4 |
| Molecular Weight | 367.32 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related alpha Standards
- Methyl 3-((3-(trifluoromethyl)benzyl)oxy)thieno[2,3-b]pyridine-2-carboxylate (CAS 338419-35-5)
- 2,5-Bis(3-(trifluoromethyl)phenyl)pyridine (CAS 1261817-81-5)
- 3-(2,4-Bis(trifluoromethyl)phenyl)-5-phenylpyridine (CAS 1333319-74-6)
- 1-(3-(Trifluoromethyl)-1H-pyrazol-1-yl)-3-((4-(trifluoromethyl)benzyl)amino)propan-2-ol (CAS 680594-01-8)
- 2-(2-(3-Methyl-5-(trifluoromethyl)-1H-pyrazol-1-yl)-4-phenylthiazol-5-yl)acetic acid (CAS 955976-94-0)
- 2-(3-Methyl-5-(trifluoromethyl)-1H-pyrazol-1-yl)-N-(pyridin-3-ylmethyl)thiazole-4-carboxamide (CAS 957039-48-4)
- 4-(4-(3-(Trifluoromethyl)phenyl)-1H-pyrazol-1-yl)benzenesulfonamide (CAS 955963-64-1)
- 2,4-Bis(trifluoromethyl)-1,1,1,2,4,5,5,5-octafluoro-3-pentanol (CAS 918-49-0)
Recommended Standards
- (S)-2-(((Benzyloxy)carbonyl)amino)-3-(3-(trifluoromethyl)phenyl)propanoic acid (CAS 1270285-74-9)
- (E)-N-(2,4-dimethoxyphenyl)-3-(4-(trifluoromethoxy)phenyl)acrylamide (CAS 882082-42-0)
- (R)-3-(((benzyloxy)carbonyl)amino)-4-(2,4,5-trifluorophenyl)butanoic acid (CAS 1246960-25-7)
- (S)-2-(((benzyloxy)carbonyl)amino)-3-(4-(trifluoromethyl)phenyl)propanoic acid (CAS 921623-47-4)
- 3-Methyl-7-(3-phenylpropyl)-8-(piperazin-1-yl)-3,7-dihydro-1H-purine-2,6-dione (CAS 353255-08-0)
- (2-Methyl-2H-indazol-4-yl)methanamine (CAS 1159511-62-2)
- (S)-2-(((1-Benzylpyrrolidin-2-yl)methyl)(cyclopropyl)amino)acetic acid (CAS 1354019-89-8)
- N-(2-chlorophenyl)-N-tosylglycine (CAS 333459-19-1)
- 2-Fluoro-4-(methoxycarbonyl)benzoic Acid (CAS 314241-04-8)
- 2-(Difluoromethyl)benzo[d]oxazole-7-acetic acid (CAS 1804079-81-9)
- (4-(4-Nitrophenoxy)phenyl)methanamine (CAS 91955-44-1)
- 2,3-Dihydro-[2,2'-bipyridin]-4(1H)-one (CAS 827622-89-9)
- N-(3-Isobutoxybenzyl)-2-propanamine (CAS 1040683-53-1)
- Semaglutide-d5 (CAS CATO-C4X-2226153)
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