Candesartan-d5 Methyl Ester CAS 1216502-48-5
| CAS No. | 1216502-48-5 |
| Molecular Formula | - |
| Molecular Weight | 459.51 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies Candesartan-d5 Methyl Ester (CAS 1216502-48-5), a certified reference material (molecular formula C25H17D5N6O3, MW 459.51 g/mol) for analytical method development and quality control.
The molecular framework of Candesartan-d5 Methyl Ester (C25H17D5N6O3) is characterized by deuterium isotope labeling, a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Candesartan-d5 Methyl Ester meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C25H17D5N6O3 |
| Molecular Weight | 459.51 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 20.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Nitrogen Atoms | 6 |
Related Candesartan Standards
- Candesartan Cilexetil EP Impurity I (CAS 139481-69-9)
- Candesartan Cilexetil Impurity 43 (CAS CATO-C4X-123443)
- Candesartan Cilexetil EP Impurity A (CAS 139481-58-6)
- Candesartan N2-Ethyl Impurity (CAS 1246819-02-2)
- Candesartan N1-Ethyl Impurity (CAS 1246817-38-8)
- Candesartan-d5 (CAS 1189650-58-5)
- Candesartan Cilexetil EP Impurity G-d4 (CAS 1346604-70-3)
- Candesartan Ethyl Ester Desethyl Analog (CAS 1225044-20-1)
Recommended Standards
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- Q-Peptide trifluoroacetate salt (CAS 1361235-89-3)
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