6-Isopropyl-2-(5-nitrothiophene-2-carboxamido)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxamide hydrochloride CAS 1216751-16-4
| CAS No. | 1216751-16-4 |
| Molecular Formula | C16H18N4O4S2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 6-Isopropyl-2-(5-nitrothiophene-2-carboxamido)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxamide hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies 6-Isopropyl-2-(5-nitrothiophene-2-carboxamido)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxamide hydrochloride (CAS 1216751-16-4), a certified reference material (molecular formula C16H18N4O4S2HCl, MW 430.92 g/mol) for analytical method development and quality control.
The molecular framework of 6-Isopropyl-2-(5-nitrothiophene-2-carboxamido)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxamide hydrochloride (C16H18N4O4S2HCl) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C16H18N4O4S2 HCl |
| Molecular Weight | 430.92 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 2 |
Related Isopropyl Standards
- 6-Isopropyl-4-nitro (1H)Indazole (CAS 1000340-87-3)
- 1-Isopropyl-2-methoxy-3-nitrobenzene (CAS 1000342-22-2)
- 6-Isopropyl-1H-indol-4-amine (CAS 1000343-80-5)
- Isopropyl 1-(4-chlorophenyl)-5-oxo-2,5-dihydro-1H-1,2,4-triazole-3-carboxylate (CAS 1000574-54-8)
- Isopropyl 1-(3,4-dichlorophenyl)-5-oxo-2,5-dihydro-1H-1,2,4-triazole-3-carboxylate (CAS 1000574-60-6)
- Isopropyl 5-oxo-1-(3-(trifluoromethyl)phenyl)-2,5-dihydro-1H-1,2,4-triazole-3-carboxylate (CAS 1000574-65-1)
- Isopropyl 5-oxo-1-(m-tolyl)-2,5-dihydro-1H-1,2,4-triazole-3-carboxylate (CAS 1000574-70-8)
- 1000576-15-7 Isopropyl 2-[2-(4-bromophenyl)hydrazono]-2-chloroacetate MFCD09877871 (CAS 1000576-15-7)
Recommended Standards
- Ethyl 3-(4-chlorophenyl)-5-hydroxy-1,2,4-triazine-6-carboxylate (CAS 36286-77-8)
- 2-(6-Oxo-4-phenyl-1,6-dihydropyrimidin-2-yl)-2,3,4,5,6,7-hexahydro-1H-indazol-3-one (CAS 210417-30-4)
- 5-(Difluoromethyl)-3-(trifluoromethyl)pyridin-2-amine (CAS 1806768-24-0)
- 1-(5-Hydroxybenzo[c][1,2,5]thiadiazol-4-yl)ethanone (CAS 120893-39-2)
- 1-(2-Bromo-4-methylphenyl)urea (CAS 1016706-21-0)
- 3,5-Bis(trimethylsilyl)isonicotinonitrile (CAS 827616-49-9)
- Ethyl 4-chloro-8-iodo-7-methylpyrazolo[1,5-a][1,3,5]triazine-2-carboxylate (CAS 2365243-37-2)
- 4,6-Dimethyl-1-(((5-methylfuran-2-yl)methylene)amino)-2-oxo-1,2-dihydropyridine-3-carbonitrile (CAS 349475-61-2)
- 5-Amino-1-phenyl-2',3',5',6'-tetrahydrospiro[indoline-3,4'-pyran]-2-one (CAS 1422068-78-7)
- Semaglutide impurity 260 (CAS CATO-C4X-2226260)
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