(2-Fluoro-5-isobutoxyphenyl)boronic acid CAS 1217500-65-6
| CAS No. | 1217500-65-6 |
| Molecular Formula | C10H14BFO3 |
| Molecular Weight | 212.03 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(2-Fluoro-5-isobutoxyphenyl)boronic acid (CAS 1217500-65-6), molecular formula C10H14BFO3 and molecular weight 212.03 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of (2-Fluoro-5-isobutoxyphenyl)boronic acid (C10H14BFO3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H14BFO3 |
| Molecular Weight | 212.03 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
Related Fluoro Standards
- (2-Fluoro-3-isobutoxyphenyl)boronic acid (CAS 1217500-66-7)
- (5-Fluoro-2-(isopropoxymethyl)phenyl)boronic acid (CAS 1333392-80-5)
- (2-Fluoro-5-(isopropoxymethyl)phenyl)boronic acid (CAS 1334681-94-5)
- (3-Fluoro-5-(isopropoxymethyl)phenyl)boronic acid (CAS 1704063-75-1)
- (4-Fluoro-3-(isopropoxymethyl)phenyl)boronic acid (CAS 1704063-98-8)
- (4-Fluoro-3-methyl-5-propoxyphenyl)boronic acid (CAS 2096338-73-5)
- (4-Fluoro-5-isopropyl-2-methoxyphenyl)boronic acid (CAS 875446-29-0)
- 2-Fluoro-3-isopropoxy-5-methylphenylboronic acid (CAS 2096336-18-2)
Recommended Standards
- 2-(iodomethyl)-2-methyloxetane (CAS 121137-98-2)
- 3-(Iodomethyl)-3-methyloxetane (CAS 112823-30-0)
- (1E,3R)-1-Iodo-1-penten-3-ol (CAS 126641-06-3)
- (4-Butoxy-2-fluorophenyl)boronic acid (CAS 1107603-52-0)
- 5-Bromo-2-Iodopyrimidine (CAS 183438-24-6)
- tert-Butyl 1-cyclohexylpiperidin-4-ylcarbamate (CAS 1286265-91-5)
- (E)-3-Methyl-4-phenylbut-3-en-2-one (CAS 42968-14-9)
- 2-(Aminomethyl)-3-(difluoromethyl)-4-(trifluoromethyl)pyridine-5-sulfonamide (CAS 1361702-20-6)
- n-(2,3-Dimethylphenyl)-3,5-dimethylisoxazole-4-carboxamide (CAS 357326-67-1)
- N-Benzyl-6-chloro-N-methyl-2-pyridinamine (CAS 1219972-10-7)
- a-Me-Phe(2-NO2)-OH·H2O (CAS 1241680-71-6)
- (2R,4R,5S)-tert-butyl 5-ethyl-2-(2-hydroxyethyl)piperidine-4-carboxylate (CAS 1417788-94-3)
- 1-(2,6-difluorophenyl)guanidine hydrochloride (CAS 112677-41-5)
- Semaglutide impurity 87 (CAS CATO-C4X-222687)
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