Semaglutide impurity 87 CAS CATO-C4X-222687

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-222687
Molecular FormulaC20H37N3O12
Molecular Weight511.52 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Semaglutide impurity 87 CAS CATO-C4X-222687 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 511.52 g/mol gives Semaglutide impurity 87 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Semaglutide impurity 87 (CAS CATO-C4X-222687) is a certified pharmaceutical impurity reference standard with the molecular formula C20H37N3O12 and a molecular weight of 511.52 g/mol.

Semaglutide impurity 87 (C20H37N3O12) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC20H37N3O12
Molecular Weight511.52 g/mol
AppearanceOff-white to pale yellow crystalline powder
Purity97%+
StorageStore in a cool place (≤25°C), protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Nitrogen Atoms3

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