2-Demethyl Colchicine-d3 CAS 1217630-52-8
| CAS No. | 1217630-52-8 |
| Molecular Formula | - |
| Molecular Weight | 388.43 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-Demethyl Colchicine-d3 is closely related to deuterium isotope labeling, a flavonoid core, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2-Demethyl Colchicine-d3 (CAS 1217630-52-8) is a high-purity analytical reference standard with the molecular formula C21H20D3NO6 and a molecular weight of 388.43 g/mol.
The molecular framework of 2-Demethyl Colchicine-d3 (C21H20D3NO6) is characterized by deuterium isotope labeling, a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-Demethyl Colchicine-d3 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H20D3NO6 |
| Molecular Weight | 388.43 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Nitrogen Atoms | 1 |
Related Demethyl Standards
- 3-Demethyl Colchicine-d3 (CAS 1314417-96-3)
- 2-Demethyl Colchicine (CAS 102491-80-5)
- 2-Demethyl Colchicine (CAS 7336-36-9)
- Demethyl Naproxen Acyl-β-D-glucuronide (CAS 91488-21-0)
- 4-Demethyl Daunomycinone (CAS 52744-22-6)
- N Demethyl Trimebutine Hydrochloride D9 (CAS CATO-C4X-185825)
- 7-O-Demethyl a-Narcotine (CAS 68353-55-9)
- 3-Demethyl Thiocolchicine-d3 (CAS 1246818-03-0)
Recommended Standards
- H-Gly-Arg-AMC (CAS 65147-19-5)
- Colchiceine-d3 (CAS 1217695-72-1)
- Momelotinib impurity 6 (CAS CATO-C4X-33776)
- Ozagrel Impurity 20 (CAS CATO-C4X-197120)
- (2-Chlorothiophen-3-yl)methanol (CAS 105114-80-5)
- 6-{5,11-dioxo-5H,6H,6aH,11H-isoindolo[2,1-a]quinazolin-6-yl}hexanoic acid (CAS 1630763-33-5)
- 4-Amino-1-(2-(diethylamino)ethyl)-2,5-dihydro-1H-pyrrole-3-carbonitrile (CAS 1707563-97-0)
- 3-[(1-Phenylethyl)amino]propanamide (CAS 740019-35-6)
- 3-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-methyl-1,2,4-oxadiazol-5-amine (CAS 1823183-49-8)
- N-(4-bromophenyl)-4-chloro-N-(3-nitrobenzyl)benzamide (CAS 332163-55-0)
- Aripiprazole Impurity 43 (CAS 54147-91-0)
- Gatifloxacin Sesquihydrate (CAS 180200-66-2)
- Perfluorobutanoic acid sodium (CAS 2218-54-4)
- MOTS-c Peptide (CAS 1627580-64-6)
Why CATO?
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