Tenofovir disoproxil Impurity 122 CAS 1217630-57-3
| CAS No. | 1217630-57-3 |
| Molecular Formula | C13H22N5O4P |
| Molecular Weight | 343.32 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Tenofovir disoproxil Impurity 122 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
As a process- or degradation-related impurity, Tenofovir disoproxil Impurity 122 (CAS 1217630-57-3, C13H22N5O4P) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage, Tenofovir disoproxil Impurity 122 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 343.32 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C13H22N5O4P |
| Molecular Weight | 343.32 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Nitrogen Atoms | 5 |
Related Tenofovir Standards
- Tenofovir disoproxil Impurity 55 (CAS 180587-75-1)
- Tenofovir Impurity 113 (CAS 1335287-28-9)
- Tenofovir disoproxil Impurity 115 (CAS CATO-C4X-1076115)
- Tenofovir Disoproxil Impurity 46 (CAS CATO-C4X-107646)
- Tenofovir disoproxil Impurity 124 (CAS CATO-C4X-1076124)
- Tenofovir Impurity 64 (CAS CATO-C4X-107664)
- Tenofovir Alafenamide Impurity 23 (CAS CATO-C4X-179723)
- Tenofovir Alafenamide Impurity 18 (CAS 379270-35-6)
Recommended Standards
- (2S,4S)-1-(tert-Butoxycarbonyl)-4-(2,4-difluoro-phenoxy)-2-pyrrolidinecarboxylic acid 317357-33-8 (CAS 317357-33-8)
- N-(4-((3-(trifluoromethyl)phenyl)sulfonyl)phenyl)acetamide (CAS 339105-01-0)
- Bauhinin (CAS 100757-58-2)
- N-(3-acetylphenyl)-4-(trifluoromethyl)benzenesulfonamide (CAS 338966-26-0)
- Terbutaline Impurity 21 (CAS CATO-C4X-118321)
- Atrasentan Impurity 171 (CAS 1059051-90-9)
- Oseltamivir Impurity 251 (CAS CATO-C4X-1720251)
- Acetylcysteine Impurity 4 (CAS 210354-22-6)
- 2-Methyl-3-oxo-4-phenyl-2,3-dihydrofuran-2-yl acetate (CAS 192451-60-8)
- 2-(2-Bromo-4-formyl-6-methoxyphenoxy)acetamide (CAS 692268-00-1)
- 3,4-Dimethyl-5-(thiophen-2-yl)isoxazole (CAS 56421-65-9)
- 3-[5-Chloro-2-(2-propynyloxy)phenyl]acrylic acid (CAS 695186-82-4)
- 6-Fluoro-8-nitrochroman (CAS 282547-27-7)
- Insulin Glargine (CAS 160337-95-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com