(R)-5-Chloro-α-(cyclopropylethynyl)-2-[[(4-methoxyphenyl)methyl]amino]-α-(trifluoromethyl)benzenemethanol CAS 1217701-95-5
| CAS No. | 1217701-95-5 |
| Molecular Formula | C21H19ClF3NO2 |
| Molecular Weight | 409.83 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 409.83 g/mol gives (R)-5-Chloro-α-(cyclopropylethynyl)-2-[[(4-methoxyphenyl)methyl]amino]-α-(trifluoromethyl)benzenemethanol distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
(R)-5-Chloro-α-(cyclopropylethynyl)-2-[[(4-methoxyphenyl)methyl]amino]-α-(trifluoromethyl)benzenemethanol (CAS 1217701-95-5), molecular formula C21H19ClF3NO2 and molecular weight 409.83 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, (R)-5-Chloro-α-(cyclopropylethynyl)-2-[[(4-methoxyphenyl)methyl]amino]-α-(trifluoromethyl)benzenemethanol is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 409.83 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures (R)-5-Chloro-α-(cyclopropylethynyl)-2-[[(4-methoxyphenyl)methyl]amino]-α-(trifluoromethyl)benzenemethanol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H19ClF3NO2 |
| Molecular Weight | 409.83 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related R Standards
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- 2-({5-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]pyrimidin-2-yl}sulfanyl)-1-phenylethan-1-one (CAS 344263-20-3)
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- 3-((3-Chloro-4-fluorophenyl)sulfonyl)-7-(diethylamino)-2H-chromen-2-one (CAS 904438-94-4)
- Ethyl 2-((2-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-5-fluoro-6-methylpyrimidin-4-yl)thio)acetate (CAS 1823183-41-0)
- 4-Chloro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidine (CAS 1830311-70-0)
- 1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-N-[(4-methoxyphenyl)methyl]-1H-pyrrole-2-carboxamide (CAS 338397-63-0)
- 3-Chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-7-[[2-(trimethylsilyl)ethoxy]methyl]-7H-pyrrolo[2,3-c]pyridazine (CAS 2773461-58-6)
Recommended Standards
- 6-[1-(3-Chlorophenyl)-1H-pyrazol-5-yl]-2-(3-methoxyphenyl)-4-methyl-2,3,4,5-tetrahydro-1,2,4-triazine-3,5-dione (CAS 321538-33-4)
- 4-(4-Chlorobenzoyl)-1-(furan-2-ylmethyl)-3-hydroxy-5-(3-hydroxyphenyl)-1H-pyrrol-2(5H)-one (CAS 618074-52-5)
- Telantinib (CAS 332012-40-5)
- 3-(2-Chlorophenyl)-N-{[3-(4-methoxyphenyl)-1,2-oxazol-5-yl]methyl}-1,2-oxazole-5-carboxamide (CAS 338750-11-1)
- Selonsertib (CAS 1448428-04-3)
- 2-chloro-6-(2-chlorophenyl)pyridine (CAS 557111-94-1)
- Potassium but-2-ynedioate (CAS 14341-52-7)
- O-Butyl Dabigatran Ethyl Ester (Dabigatran Impurity) (CAS 1416446-43-9)
- 2-(Ethylthio)-3-(1-methylpiperidin-2-yl)pyridine (CAS 1352539-11-7)
- 3-(1H-Imidazol-2-yl)propan-1-ol (CAS 1314965-15-5)
- 5H-pyrrolo[2,3-b]pyrazine-6-carbonitrile (CAS 1503470-78-7)
- 1-Benzyl-2,6-dioxo-N-(4-(trifluoromethoxy)phenyl)-1,2,3,6-tetrahydropyrimidine-4-carboxamide (CAS 338412-65-0)
- 4-[(propan-2-yl)carbamoyl]butanoic acid (CAS 59481-43-5)
- Tirzepatide Impurity 14 (CAS CATO-C4X-324014)
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