3-Chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-7-[[2-(trimethylsilyl)ethoxy]methyl]-7H-pyrrolo[2,3-c]pyridazine CAS 2773461-58-6
| CAS No. | 2773461-58-6 |
| Molecular Formula | C18H29BClN3O3Si |
| Molecular Weight | 409.79 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 3-Chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-7-[[2-(trimethylsilyl)ethoxy]methyl]-7H-pyrrolo[2,3-c]pyridazine (CAS 2773461-58-6), a certified reference material (molecular formula C18H29BClN3O3Si, MW 409.79 g/mol) for analytical method development and quality control.
The molecular framework of 3-Chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-7-[[2-(trimethylsilyl)ethoxy]methyl]-7H-pyrrolo[2,3-c]pyridazine (C18H29BClN3O3Si) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H29BClN3O3Si |
| Molecular Weight | 409.79 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2003 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- Ethyl 2-((2-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-5-fluoro-6-methylpyrimidin-4-yl)thio)acetate (CAS 1823183-41-0)
- 4-Chloro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidine (CAS 1830311-70-0)
- 1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-N-[(4-methoxyphenyl)methyl]-1H-pyrrole-2-carboxamide (CAS 338397-63-0)
- 2-({5-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]pyrimidin-2-yl}sulfanyl)-1-phenylethan-1-one (CAS 344263-20-3)
- (4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)(2-phenylcyclopropyl)methanone (CAS 1024113-34-5)
- (R)-5-Chloro-α-(cyclopropylethynyl)-2-[[(4-methoxyphenyl)methyl]amino]-α-(trifluoromethyl)benzenemethanol (CAS 1217701-95-5)
- 3-Chloro-2-({4-[(5-nitropyridin-2-yl)oxy]phenyl}methyl)-5-(trifluoromethyl)pyridine (CAS 338393-30-9)
- 5-Benzyl-3-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-3aH,4H,5H,6H,6aH-pyrrolo[3,4-d][1,2]oxazole-4,6-dione (CAS 339030-07-8)
Recommended Standards
- 2-Bromo-3,5-diiodopyridine (CAS 885952-14-7)
- Zinc acexamate CRS (CAS 70020-71-2)
- 1,3-Diethyl 2-{[(2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}ethyl)amino]methylidene}propanedioate (CAS 337920-38-4)
- Sitafloxacin Isomer Impurity 3(SSR) (CAS 127254-11-9)
- Ethyl 5-oxo-4,5-dihydro-1H-pyrazole-3-carboxylate (CAS 58607-90-2)
- 4-((2-(4-(Hydroxymethyl)piperidin-1-yl)benzyl)amino)-3-nitrobenzonitrile (CAS 860611-01-4)
- 3-Benzyl 7-tert-butyl 9,9-difluoro-3,7-diaza-bicyclo[3.3.1]nonane-3,7-dicarboxylate (CAS 1823424-25-4)
- 6-Chloro-3-(difluoromethyl)-5-iodopyridine-2-sulfonamide (CAS 1805390-59-3)
- Strontium hydride (99.5%-Sr) (CAS 13598-33-9)
- 2-(1,3-Benzoxazol-2-ylsulfanyl)-N-(3,4-dichlorophenyl)acetamide (CAS 297150-39-1)
- 2-(4-(tert-Butyl)phenyl)-6-chloropyrazine (CAS 943997-52-2)
- 2,4-Dichloro-6-(trifluoromethyl)pyridin-3-ol (CAS 1214361-93-9)
- 3-Bromo-6-(difluoromethyl)-5-iodopyridin-2-amine (CAS 1805287-30-2)
- Liraglutide Impurity 13 TFA Salt (CAS CATO-C4X-199213)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com