(S)-1-(tert-Butoxycarbonyl)-2-(2-(trifluoromethyl)-benzyl)pyrrolidine-2-carboxylic acid CAS 1217741-53-1
| CAS No. | 1217741-53-1 |
| Molecular Formula | C18H22F3NO4 |
| Molecular Weight | 373.37 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), (S)-1-(tert-Butoxycarbonyl)-2-(2-(trifluoromethyl)-benzyl)pyrrolidine-2-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
(S)-1-(tert-Butoxycarbonyl)-2-(2-(trifluoromethyl)-benzyl)pyrrolidine-2-carboxylic acid (CAS 1217741-53-1), molecular formula C18H22F3NO4 and molecular weight 373.37 g/mol, is a CATO reference standard with documented purity and traceability.
(S)-1-(tert-Butoxycarbonyl)-2-(2-(trifluoromethyl)-benzyl)pyrrolidine-2-carboxylic acid (C18H22F3NO4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C18H22F3NO4 |
| Molecular Weight | 373.37 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- Boc-(S)-α-(4-trifluoromethylbenzyl)-Pro-OH (CAS 1217720-94-9)
- (S)-1-(tert-Butoxycarbonyl)-2-(3-(trifluoromethyl)-benzyl)pyrrolidine-2-carboxylic acid (CAS 1217832-93-3)
- 1-(Tert-butoxycarbonyl)-4-(2-(trifluoromethyl)phenyl)piperidine-4-carboxylic acid (CAS 1211534-42-7)
- 2-(4-Fluorophenyl)-2-oxoethyl 2-(((benzyloxy)carbonyl)amino)-2-methylpropanoate (CAS 1261118-01-7)
- 2-cyclobutoxy-4,6-dimethylpyridine-3-carbonitrile (CAS 1247157-16-9)
- N-Butyl-3-(2-hydrazinyl-2-oxoethoxy)benzamide (CAS 1820735-59-8)
- 3-(hydroxyimino)-6-methyl-3,4-dihydro-2H-benzo[b][1,4]oxazin-2-one (CAS 937602-17-0)
- Isopropyl 4-hydroxy-3,3-dimethylbutanoate (CAS 1803586-43-7)
- 2-amino-N-(2-hydroxyethyl)benzamide hydrochloride (CAS 34637-48-4)
- (2E)-3-(3-BRomo-4-fluorophenyl)-2-propenoic acid, methyl ester (CAS 959961-64-9)
- Nintedanib Impurity 10 (CAS 2037385-84-3)
- Dichloromethanesulfinyl chloride (CAS 62479-74-7)
- 4-(2-Aminoethyl)-3,5-dimethyl-1-[(4-methylbenzene)sulphonyl]-1H-pyrazole (CAS 1001560-08-2)
- Antifreeze Polypeptide 6 (winter flounder) trifluoroacetate salt (CAS 122604-16-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com