((2R,5R)-5-(6-Amino-9H-purin-9-yl)-3-fluoro-2,5-dihydrofuran-2-yl)methanol CAS 121850-90-6
| CAS No. | 121850-90-6 |
| Molecular Formula | C10H10FN5O2 |
| Molecular Weight | 251.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including ((2R,5R)-5-(6-Amino-9H-purin-9-yl)-3-fluoro-2,5-dihydrofuran-2-yl)methanol.
CATO supplies ((2R,5R)-5-(6-Amino-9H-purin-9-yl)-3-fluoro-2,5-dihydrofuran-2-yl)methanol (CAS 121850-90-6), a certified reference material (molecular formula C10H10FN5O2, MW 251.22 g/mol) for analytical method development and quality control.
((2R,5R)-5-(6-Amino-9H-purin-9-yl)-3-fluoro-2,5-dihydrofuran-2-yl)methanol (C10H10FN5O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H10FN5O2 |
| Molecular Weight | 251.22 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 5 |
Recommended Standards
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- 1-(5-amino-8-fluoro-2,3,4,5-tetrahydro-1H-2-benzazepin-2-yl)ethan-1-one hydrochloride (CAS 1803599-65-6)
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- Tirzepatide Impurity 47 (CAS CATO-C4X-324047)
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