Carbamazepine EP Impurity C CAS 1219170-51-0
| CAS No. | 1219170-51-0 |
| Molecular Formula | C16H13N3O2 |
| Molecular Weight | 279.29 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Carbamazepine EP Impurity C (C16H13N3O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a process- or degradation-related impurity, Carbamazepine EP Impurity C (CAS 1219170-51-0, C16H13N3O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H13N3O2 |
| Molecular Weight | 279.29 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Nitrogen Atoms | 3 |
Related Carbamazepine Standards
- Carbamazepine Impurity 16 (CAS CATO-C4X-118116)
- Carbamazepine Impurity 26 (CAS CATO-C4X-118126)
- Carbamazepine Impurity 37 (CAS CATO-C4X-118137)
- Carbamazepine Impurity 24 (CAS CATO-C4X-118124)
- Carbamazepine Impurity N9 (CAS 16968-19-7)
- Carbamazepine Impurity 13 (CAS 75272-34-3)
- Carbamazepine Impurity 36 (CAS 35079-97-1)
- Carbamazepine Impurity 18 (CAS CATO-C4X-118118)
Recommended Standards
- Hydrochlorothiazide Impurity 20 (CAS 82205-98-9)
- Roxatidine impurity 70 (CAS CATO-C4X-121370)
- (S)-3-amino-4-((S)-1-amino-1-oxo-3-phenylpropan-2-ylamino)-4-oxobutanoic acid 5241-71-4 L-Aspartic acid-L-phenylalanine amide (CAS 5241-71-4)
- Isavuconazole Impurity 7 (CAS 2733698-17-2)
- Dopamine Impurity 33 (CAS CATO-C4X-190833)
- Beraprost Impurity 26 (CAS CATO-C4X-218426)
- Lidocaine Impurity 49 (CAS 81-20-9)
- 5-((4-Bromophenyl)sulfonyl)-N-methyl-1,2,3-thiadiazole-4-carboxamide (CAS 339107-83-4)
- (R)-2-(Boc-amino)-3-buten-1-ol (CAS 89985-86-4)
- 5-(((2-Chlorothiazol-5-yl)methyl)thio)-1,3,4-thiadiazol-2-amine (CAS 439110-88-0)
- Vardenafil Impurity 59 (CAS CATO-C4X-101759)
- Methyl 4-bromo-3-(4-fluorophenyl)-1h-pyrazole-5-carboxylate (CAS 1350465-88-1)
- 1-(1-Methyl-1h-benzo[d]imidazol-2-yl)ethane-1-thiol (CAS 1038982-09-0)
- Insulin Degludec Impurity 17 (CAS CATO-C4X-215717)
Why CATO?
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