Hydrochlorothiazide Impurity 20 CAS 82205-98-9
| CAS No. | 82205-98-9 |
| Molecular Formula | C7H9N3O5S2 |
| Molecular Weight | 279.29 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Hydrochlorothiazide Impurity 20 (C7H9N3O5S2) contains an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 279.29 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies Hydrochlorothiazide Impurity 20 (CAS 82205-98-9), a pharmacopoeial impurity reference standard (molecular formula C7H9N3O5S2, MW 279.29 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Hydrochlorothiazide Impurity 20 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H9N3O5S2 |
| Molecular Weight | 279.29 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1980 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 2 |
Related Hydrochlorothiazide Standards
- Hydrochlorothiazide EP Impurity B (CAS 121-30-2)
- Hydrochlorothiazide impurity 44 (CAS CATO-C4X-117744)
- Hydrochlorothiazide Impurity 52 (CAS CATO-C4X-117752)
- Hydrochlorothiazide Impurity 13 (CAS 99418-26-5)
- Hydrochlorothiazide Impurity 22 (CAS 90794-87-9)
- Hydrochlorothiazide Impurity 19 (CAS 85119-88-6)
- Hydrochlorothiazide Impurity 56 (CAS CATO-C4X-117756)
- Hydrochlorothiazide Impurity 9 (CAS 364-96-5)
Recommended Standards
- (S)-3-amino-4-((S)-1-amino-1-oxo-3-phenylpropan-2-ylamino)-4-oxobutanoic acid 5241-71-4 L-Aspartic acid-L-phenylalanine amide (CAS 5241-71-4)
- Carbamazepine EP Impurity C (CAS 1219170-51-0)
- 304887-17-0 4-Oxo-4-{[4-(propoxycarbonyl)phenyl]amino}butanoic acid MFCD01055660 (CAS 304887-17-0)
- Roxatidine impurity 70 (CAS CATO-C4X-121370)
- Risperidone Impurity 20 (CAS 1172297-96-9)
- Alogliptin Impurity 37 (CAS 22115-41-9)
- Coclaurine Impurity 2 HCl (CAS 13233-00-6)
- 3-Amino-4-chloro-N,N-dimethylbenzamide (CAS 51919-89-2)
- Cobimetinib (racemate) (CAS 934662-91-6)
- 2-Amino-3-methoxybenzenethiol hydrochloride (CAS 68834-70-8)
- 2-[(3R)-6,6-dimethylmorpholin-3-yl]ethanol (CAS 1639482-73-7)
- 4-((5-Chloro-6-oxo-1-(p-tolyl)-1,6-dihydropyridazin-4-yl)oxy)-3-ethoxybenzaldehyde (CAS 881580-97-8)
- Rimegepant Impurity 22 (CAS CATO-C4X-248722)
- 263251-78-1 NMG938VJ6T D-3 Tavilermide [USAN:INN] UNII-NMG938VJ6T MIM-D3 MIM-D 3 D 3 (peptide) Tavilermide (CAS 263251-78-1)
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