Ethyl 2-(2,4-difluorophenyl)nicotinate CAS 1219503-87-3
| CAS No. | 1219503-87-3 |
| Molecular Formula | C14H11F2NO2 |
| Molecular Weight | 263.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Ethyl 2-(2,4-difluorophenyl)nicotinate (CAS 1219503-87-3), a certified reference material (molecular formula C14H11F2NO2, MW 263.24 g/mol) for analytical method development and quality control.
Structurally, Ethyl 2-(2,4-difluorophenyl)nicotinate (C14H11F2NO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 263.24 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H11F2NO2 |
| Molecular Weight | 263.24 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Ethyl Standards
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Recommended Standards
- Methyl 6-(2,6-difluoro-3-methylphenyl)picolinate (CAS 1210419-50-3)
- 6,6-Difluoro-4-(isobutoxycarbonyl)-2-azabicyclo[3.1.0]Hexane-2-carboxylic acid (CAS 1258639-92-7)
- 3-(2-Fluoro-4-sulfamoylphenoxy)propanoic acid (CAS 1152864-98-6)
- (2-(Difluoromethoxy)-3-methylphenyl)(pyridin-4-yl)methanone (CAS 1261458-89-2)
- (4aS,7aS)-Hexahydro-5H-[1,4]dioxino[2,3-c]pyrrole (CAS 1462360-17-3)
- [3-(methanesulfonylmethyl)phenyl]methanamine (CAS 1235439-51-6)
- 3-Bromo-4-(pyrrolidin-3-yloxy)pyridine dihydrochloride (CAS 2379946-70-8)
- 5-Bromo-1-(2,6-difluoro-4-(trifluoromethyl)phenoxy)-2,3-difluorobenzene (CAS 2244086-34-6)
- (S)-tert-Butyl ethyl(1-(2-hydroxyethyl)pyrrolidin-3-yl)carbamate (CAS 1354003-22-7)
- 7-Bromo-6,8-dichloro-[1,3]dioxolo[4,5-g]quinoline (CAS 1447962-07-3)
- 1,8-Naphthyridine-4-carbonitrile (CAS 1142927-41-0)
- 5147-80-8 InChI=1/C6H6N2S2/c1-9-6(10-2)5(3-7)4-8/h1-2H [bis(methylthio)methylene]malononitrile propanedinitrile, [bis(methylthio)methylene]- (CAS 5147-80-8)
- 3-Aminothietane 1,1-Dioxide Hydrochloride (CAS 1422344-24-8)
- Semaglutide Impurity 3 (CAS CATO-C4X-22263)
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