(2-(Difluoromethoxy)-3-methylphenyl)(pyridin-4-yl)methanone CAS 1261458-89-2

Purity 97%+In StockPharmaceutical Standards
CAS No.1261458-89-2
Molecular FormulaC14H11F2NO2
Molecular Weight263.24 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(2-(Difluoromethoxy)-3-methylphenyl)(pyridin-4-yl)methanone CAS 1261458-89-2 chemical structure

Description

The occurrence of (2-(Difluoromethoxy)-3-methylphenyl)(pyridin-4-yl)methanone is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

(2-(Difluoromethoxy)-3-methylphenyl)(pyridin-4-yl)methanone (CAS 1261458-89-2) is a high-purity analytical reference standard with the molecular formula C14H11F2NO2 and a molecular weight of 263.24 g/mol.

Based on its molecular formula C14H11F2NO2, (2-(Difluoromethoxy)-3-methylphenyl)(pyridin-4-yl)methanone contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 263.24 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC14H11F2NO2
Molecular Weight263.24 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1990
Halogen ContentF-containing
Nitrogen Atoms1

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